AG Plested

Humboldt Universität zu Berlin,
Leibniz-Forschungsinstitut für Molekulare Pharmakologie &
Cluster of Excellence NeuroCure, Charité Universitätsmedizin

Robert-Rössle-Str. 10
13125 Berlin

Tel.: +49 (0) 30 94973-245 
                      -322 (Lab.)

We don't have a fax

plested [at]

Molecular Neuroscience and Biophysics (Andrew Plested)

In the Plested lab, we are interested in ion channel receptors and fast signalling in the nervous system. Receptors that are found at synapses between nerve cells have formed the backbone of our research for some years. The activation of these complex macromolecular machines is triggered by neurotransmitters in a fraction of a second. Our objective is to understand the relationship between the molecular structure of a given receptor (its shape) and its activity (what it does). More recently, we have become interested in the relation between receptor properties and synaptic signalling. 

We are members of the NeuroCure Cluster of Excellence, and the Leibniz-Institut für Molekulare Pharmakologie (FMP). Our laboratories are located in the Marthe-Vogt-Haus (Haus 81) at the Campus Berlin Buch. If you would like to contact us, please write to the email address on the right.

Latest News

26.06.17 The lab is on the move! Over the next few weeks, we will transfer to new labs in the Marthe-Vogt Haus - the main building of the FMP. 

17.02.17 Mechanism of partial agonism in AMPA-type glutamate receptors

Our paper on the relationship between partial agonists, conformational space and AMPA receptor activation is now online at Nature Communications. PDB entry is here. Congratulations to Hector, Clarissa and Miriam!

15.10.16 Sebastian Opfermann has joined us to do his PhD, studying glutamate receptors at the single channel level as part of our ERC funded project GluActive. Welcome Sebastian!

04.10.16 October seems to be Spanish month in the Plested lab. Alberto Gonzalez is visiting us from Tenerife, and Boris Bouazza is doing his first rotation of the Medical Neurosciences doctoral programme. Benvenidos a Berlín! 

20.08.16 Single Channel Recording of Ligand-Gated Ion Channels

A topic introduction and protocol for single channel recording of glycine receptors are now available as part of the Ion Channels collection at Cold Spring Harbor Lab Protocols. These articles are based on the lectures and practical course held every year at CSHL. Thanks to Jelena for help with the protocol!

Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V. (FMP)
Campus Berlin-Buch
Robert-Roessle-Str. 10
13125 Berlin, Germany
+4930 94793 - 100 
+4930 94793 - 109 (Fax)