Andrew Plested
Heisenberg Professor of Cellular Biophysics, Humboldt Universität zu Berlin


Leibniz-Forschungsinstitut für Molekulare Pharmakologie
Robert-Rössle-Str. 10
13125 Berlin

Tel.: +49 (0) 30 94793-245 
                      -322 (Lab.)

We don't have a fax

plested [at]

HiWi wanted!

The Plested lab is urgently seeking a HiWi to assist our molecular biology efforts. Please contact Andrew Plested or Marcus Wietstruk ( ) for more details about the position. Posted 170810

Molecular Neuroscience and Biophysics (Andrew Plested)

In the Plested lab, we are interested in ion channel receptors and fast signalling in the nervous system. Receptors that are found at synapses between nerve cells have formed the backbone of our research for some years. The activation of these complex macromolecular machines is triggered by neurotransmitters in a fraction of a second. Our objective is to understand the relationship between the molecular structure of a given receptor (its shape) and its activity (what it does). More recently, we have become interested in the relation between receptor properties and synaptic signalling. 

We are members of the Humboldt University Institute for Biology, the NeuroCure Cluster of Excellence, and the Leibniz-Institut für Molekulare Pharmakologie (FMP). Our laboratories are located in the Marthe-Vogt-Haus (Haus 81) at the Campus Berlin Buch. If you would like to contact us, please write to the email address on the right.

Latest News

06.11.17 Saeid Abdolvand has joined us from Iran to do his PhD work in our DFG project "Dynion" with Han Sun. Welcome to Berlin, Saeid!

08.09.17 Control of AMPA receptor activity by the extracellular loops of auxiliary proteins

It's a Doppelpack from Irene and Clarissa, this time with Anna too. It's been on BiorXiv for a few months, but the final version of our latest  paper revealing mechanisms of glutamate receptor modulation is now out at eLife. Congrats to everyone.

02.09.17 Unitary Properties of AMPA Receptors with Reduced Desensitization

Our collaborative paper with Jim Howe and Wei Zhang, revealing unexpected mechanisms of desensitization in AMPA receptors, is online now at Biophysical Journal. PDB entry is here. Congrats to Clarissa and Irene. 

01.07.17 Johann Biedermann has joined the lab to do his PhD, and will be jointly supervised by Han Sun. This collaborative project is part of the DFG research group "DynIon". Welcome Johann!

26.06.17 The lab is on the move! Over the next few weeks, we will transfer to new labs in the Marthe-Vogt Haus - the main building of the FMP. 

17.02.17 Mechanism of partial agonism in AMPA-type glutamate receptors

Our paper on the relationship between partial agonists, conformational space and AMPA receptor activation is now online at Nature Communications. PDB entry is here. Congratulations to Hector, Clarissa and Miriam!

15.10.16 Sebastian Opfermann has joined us to do his PhD, studying glutamate receptors at the single channel level as part of our ERC funded project GluActive. Welcome Sebastian!


Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V. (FMP)
Campus Berlin-Buch
Robert-Roessle-Str. 10
13125 Berlin, Germany
+4930 94793 - 100 
+4930 94793 - 109 (Fax)