Contact

Andrew Plested
Heisenberg Professor of Cellular Biophysics, Humboldt Universität zu Berlin

Address:

Leibniz-Forschungsinstitut für Molekulare Pharmakologie
Marthe-Vogt-Haus
Robert-Rössle-Str. 10
13125 Berlin
Germany

Tel.: +49 (0) 30 94793-245 
                      -322 (Lab.)

We don't have a fax

plested [at] fmp-berlin.de

Molecular Neuroscience and Biophysics (Andrew Plested)

In the Plested lab, we are interested in ion channel receptors and fast signalling in the nervous system. Receptors that are found at synapses between nerve cells have formed the backbone of our research for some years. The activation of these complex macromolecular machines is triggered by neurotransmitters in a fraction of a second. Our objective is to understand the relationship between the molecular structure of a given receptor (its shape) and its activity (what it does). More recently, we have become interested in the relation between receptor properties and synaptic signalling. 

We are members of the Humboldt University Institute for Biology, the NeuroCure Cluster of Excellence, and the Leibniz-Institut für Molekulare Pharmakologie (FMP). Our laboratories are located in the Marthe-Vogt-Haus (Haus 81) at the Campus Berlin Buch. If you would like to contact us, please write to the email address on the right.

Latest News

15.5.18 Sabrina Mischke has joined us to work on glutamate receptor spectroscopy and imaging. Sabrina is a German native and a physicist by training. Welcome to Berlin, Sabrina!

1.4.18 AMPA receptors - mechanisms of auxiliary protein action

Clarissa and Andrew wrote a review about how auxiliary subunits work for a special issue of the new journal Current Opinions in Physiology. The AMPA-Receptor (structure from Twomey et al) made the cover too. 

15.3.18 Niccolo Pampaloni has joined the lab as a postdoctoral fellow. Niccolo previously studied carbon nanotubes and their interactions with neurons at SISSA in Italy, and returns the lab to its normal resting potential of at least 2 Italians. Benvenuti a Berlino, Niccolo!

15.2.18 Iva Lučić has joined our lab as a postdoctoral fellow. Iva won a Marie Skłodowska-Curie Fellowship to study kinases and their relation to neurotransmission, as part of the DFG project TRR 186. Iva is our first Serbian lab member. Welcome to Berlin!

21.12.17Neurotransmitter Funneling Optimizes Glutamate Receptor Kinetics

Our computational and physiological study of glutamate binding to the AMPA receptor is online. Congratulations to Héctor and our collaborators Alvin Yu and Albert Lau from Johns Hopkins, USA. It's full open access, funded by the ERC project "GluActive". Check the movies, for example, glutamate binding to the receptor in the crystallographic conformation. This paper was recommended by F1000.

 

Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V. (FMP)
Campus Berlin-Buch
Robert-Roessle-Str. 10
13125 Berlin, Germany
+4930 94793 - 100 
+4930 94793 - 109 (Fax)
info(at)fmp-berlin.de

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