Contact

Dr. Alexey Ponomarenko
Dr. Tatiana Korotkova
Tel: +49 30 450539764
Fax: +49 30 450539964

ponomarenko(at)fmp-berlin.de

korotkova(at)fmp-berlin.de

 

 

Leibniz-Institut für Molekulare Pharmakologie (FMP)
NeuroCure Exzellenzcluster 
Charité Campus Mitte
Charitéplatz 1/
Virchowweg 6 (Charité CrossOver)   
10117 Berlin
Germany

 

 

 

 

 

Behavioural Neurodynamics (Ponomarenko/Korotkova)

Research

We approach the problem of shaping animals behavior by activity of neural networks from the prospective of innate behaviors. These basic behavioral patterns and their appropriate initiation and termination according to the availability of resources and environmental cues are crucial for physiological homeostasis. Aiming to understand the adaptive control of innate behaviors by specialized neuronal groups in the hypothalamus we focus on their dynamic interactions and modulation by higher brain regions. We address this broad question for specific anatomical pathways and behaviors and apply state-of-the-art parallel unitary recording techniques in freely behaving rodents and optogenetics for cell-type- and projection-specific functional analysis.

The goal of another research direction is to gain new insights into cellular and synaptic determinants of population neuronal activity. Various periodic synchronization regimes of cortical and hippocampal networks is an emergent physiological metric for neuronal dynamics in these regions, associated cognitive functions and disorders. In cooperative projects we investigate population neuronal activity in genetic mouse models to establish the contribution of specific membrane conductancies and network pathways to the generation of network oscillations in vivo.

We gratefully acknowledge support of our research by the Leibniz Association, NeuroCure Cluster of Excellence, The Human Frontier Science Program, German-Israeli Foundation for Scientific Research and Development (GIF) and DFG funded priority program SPP 1665.

Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V. (FMP)
Campus Berlin-Buch
Robert-Roessle-Str. 10
13125 Berlin, Germany
+4930 94793 - 100 
+4930 94793 - 109 (Fax)
info(at)fmp-berlin.de