Technologieplattformen (Core Facilities)

Neue Technologien erlauben uns Aspekte des Lebens zu erforschen, die ansonsten im Verborgenen blieben. Die neuen technologischen Entwicklungen spielen eine wichtige Rolle bei der Entstehung neuer biologischer Konzepte. Unsere Technologieplattformen und unser Know-How sind in nationale und internationale Projekte eingebunden und bieten anderen Forschergruppen am Institut ihren Service an.

Core Facility: Cellular Imaging (Martin Lehmann)

Our group addresses questions of biological and pharmacological importance using the full repertoire of light microscopy techniques (confocal laser scanning microscopy, two-photon excitation, uncaging processes, FCS, FRAP, FRET, FLIM, cellular uptake of peptides, colocalisation studies, intracellular ion concentrations, protein translations studies, etc. in conjunction with the electron microscopic and electrophysiological techniques.

 

Core Facility: Cell Engineering (Ralf Schülein)

The Cell Engineering Facility uses state of the art CRISPR/Cas techniques to generate gene knock-outs and knock-ins in target cells. Please visit our homepage to get more informations. Other applications of CRISPR/Cas may be possible following consultation.

 

Core Facility: Animal Facility (Natali Wisbrun)

The Animal Facility takes care of all laboratory animals.  Our team works with standards based on directives, conventions and guidelines (3R). We do our best to support our scientists in planning their animal experiments.

Core Facility: Mass Spectrometry (Fan Liu)

The mass spectrometry facility hosts state-of-the-art infrastructure for protein characterization. This includes high-end MS technologies for protein identification, quantification, post-translational modification and interaction analysis.

Core Facility: NMR (Peter Schmieder/ Hartmut Oschkinat)

The NMR facility maintains the NMR spectrometers of the FMP and supports researchers from inside and outside the FMP in using state-of-the-art NMR spectroscopy, either solid state or solution state and either in collaborations or by providing a walk-on service for routine NMR spectroscopy.

 

Core Facility: Screening-Unit (Jens-Peter von Kries)

The Screening Unit provides a high throughput technology platform for screening compound libraries (about 60.000 cpds) and for genome-wide RNA-interference using automated microscopes or other methods. The unit manages the ChemBioNet screening collection (20.000 cpds) shared with partnering platforms within Europe.

 

Core Facility: Compound Management (Edgar Specker)
The aim of the Core Facility Compound Mangement is the production of screening plates for the primary screening at the Screening Unit, the preparation of hitpicking plates in order to conduct concentration-dependent validations of primary hits, the QC-controls of these hits and the support of users to prioritize their hit lists. 

Core Facility: Peptide Chemistry (Christian Hackenberger)

The core facility aims at providing simple synthetic peptides to FMP research groups.

Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V. (FMP)
Campus Berlin-Buch
Robert-Roessle-Str. 10
13125 Berlin, Germany
+4930 94793 - 100 
+4930 94793 - 109 (Fax)
info(at)fmp-berlin.de

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