Prof. Dr. Volker Haucke

phone +49 30 94793 100
Twitter Haucke Lab



  • Become a Haucke lab member now: Openings for PhD students and postdocs in the Haucke lab. For details click here and apply now!
  • Phantastic news! Klaas Yperman receives a prestigeous EMBO long-term fellowship!
  • Congrats to Tania on her new paper in eLife on a clathrin-independent role of the clathrin adaptor AP2 in synaptic vesicle recycling!
  • Congrats! Marijn Kuijpers investigates how different functions of Endoplasmic Reticulum play a role in nerve signal transmission & neurodegeneration and receives 1.5 million from ERCStarting Grant for the project synERgy

01/2021 A short research talk on our recently published paper in Neuron in which we discovered a surprising role for autophagy in neurons here



































































Department Molecular Pharmacology and Cell Biology (Volker Haucke)

Welcome to the Volker Haucke department!

In the Haucke laboratory we aim to understand how cellular membranes and membrane-enclosed compartments dynamically exchange materials between them and its implications for cell signaling in health and disease. Our main focus is on the endocytic and endolysosomal system that we study in genome-engineered cell lines and in nerve cells or tissue. The laboratory uses a broad range of techniques including biochemical and molecular biology approaches, super-resolution light and electron microscopy, chemical biology and screening technology, electrophysiology as well as genetic and genome engineering at the cellular or organismic levels in vivo.
The overarching goal of these studies is to provide a mechanistic understanding of the assembly of protein-lipid scaffolds that support exo-endocytosis coupling and endolysosomal functions, and to use this know-how to develop novel strategies for pharmacological or genetic interference. Our studies thereby provide important and novel insights into the molecular mechanisms underlying a broad range of diseases, including epilepsy, neurodegeneration, lysosomal disorders, myopathies and cancer.

Research within the Haucke lab can be grossly divided into two major topics:

(1)    The formation and maintenance of the presynaptic compartment and its role in synaptic neurotransmission, and

(2)    The regulation of membrane homeostasis and cell signaling in the endolysosomal system by phosphoinositides and phosphoinositide-metabolizing enzymes.



Prof. Dr. Volker Haucke
CV Volker Haucke


How to become a Haucke lab member

We always seek interested and highly motivated postdocs and master or PhD students! Please apply directly by sending an email including your CV and a letter of motivation to haucke(at)

Current vacancies include:

Video presentation of the lab's research focus: Volker Haucke explaining endosomal recycling

Video portrait of the department (in German only)

Video presentation of the Marie Skłodowska-Curie Innovative Training Network: Phd - PI3K biology in health and disease

The Department also hosts the research group of


Prof. Dr. Michael Krauß
Small GTPases in Membrane Traffic

Read more about the Krauß Lab here!

Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V. (FMP)
Campus Berlin-Buch
Robert-Roessle-Str. 10
13125 Berlin, Germany
+4930 94793 - 100 
+4930 94793 - 109 (Fax)

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