The main focus of our group is the development of solid-state magic-angle spinning (MAS) NMR methodology for structure studies of various important biological systems, in particular for structural characterisation of protein-protein interactions that are responsible for the reception and transduction of signals in biological systems. This research focuses on protein domains which recognise specific peptides on the one hand and on membrane integrated receptors and receptor-ligand complexes on the other. The department is also involved in structural genomics of soluble and membrane proteins, supported by NMR technical developments. The latter aim at higher throughput and towards concepts for structure determination of membrane proteins by solid-state NMR.
 

Protein Expression and NMR Sample Preparation

Staff scientist: Dr. Anne Diehl
 

Solid State NMR

Staff scientist: Dr. Barth van Rossum
 

NMR Facility

Solid-state NMR facility manager: Dr. Matthias Hiller