Core Facility

Peter Schmieder

NMR

Peter Schmieder

The NMR facility maintains the NMR spectrometers of the FMP and supports researchers from inside and outside the FMP in using state-of-the-art NMR spectroscopy, either solid state or solution state and either in collaborations or by providing a walk-on service for routine NMR spectroscopy.


NMR

Nuclear Magnetic Resonance Spectroscopy (NMR): The NMR facility maintains FMP’s NMR spectrometers, enabling internal and external researchers to use both solid-state and solution-state NMR spectroscopy.
NMR spectroscopy allows us to study the electronic environment of individual atoms and their interactions with neighboring atoms, for example to determine the structure and dynamics of molecules. Our facility provides the research groups with two open-access spectrometers (300 MHz and 600 MHz) for their own use. For more complex problems, we collaborate with the scientists using our NMR instruments equipped with cryoprobes. A probe suitable for 31P-NMR spectroscopy is of particular importance because the phosphorylation of different molecules is studied intensively in the Chemical Biology departments.
The solid-state spectrometers are primarily used by the Structural Biology departments to determine the structures of membrane proteins or larger aggregates. For this purpose, a wide range of field strengths and probes with different sample diameters is used. DNP (dynamic nuclear polarization) experiments can also be performed on two spectrometers. Furthermore, the facility receives requests from groups outside of the FMP, as well as from commercial companies located close to the institute. These requests are met in the form of collaborative activities or as a NMR service provided by the facility. The NMR facility also participates in the German DFG-funded G-NMR network of facilities, the iNEXT initiative, and worldwide NMR studies such as the Fab-NMR study by NIST.


Research Section

Structural Biology

Equipment


fmp600

delivered in 1995, purchased with funds from the FMP
new hardware cabinet in 2012

Magnet

Bruker, unshielded, 52 mm bore

Hardware

AV III Console
sample changer (BACS-60)

Probes

5 mm QXI, z-gradient
5mm BBFO, z-Gradient
5 mm TXI, xyz-gradients
5 mm BBI, z-gradient
8 mm TXI, z-gradient

psf600

delivered in 1999 as DRX, purchased with funds from the BMBF
upgraded to AV in 2010, cryoplattform replacement in 2011

Magnet

Bruker, shielded, 54 mm bore

Hardware

AV III Console
sample changer (BACS 60)

Probes

5 mm TXI, z-gradient
5 mm QCI Cryoprobe, z-gradient

sel600

delivered in 2008, purchased with funds from the FMP

Magnet

Bruker, shielded plus, 54 mm bore

Hardware

AV III Console
sample changer (BACS 60)

Probes

5 mm TCI Cryoprobe, z-grandient

fmp750

delivered in 1996 as a DMX, purchased with funds from the FMP
upgraded to AV in 2007

Magnet

Magnex, unshielded, 52 mm bore

Hardware

AV III Console

Probes

5 mm TXI, xyz-gradients
8 mm TXI, z-gradient
5 mm TCI Cryoprobe, z-grandient

av300

delivered in 2005, purchased with funds from the FMP, new hardware cabinet in 2016

Magnet

Bruker, shielded, 54 mm bore

Hardware

AVIII Console
sample changer (BACS 120)

Probes

5 mm QNP (13C, 19F, 31P), z-gradient
5mm BBFO, z-Gradient

photo of spectrometer fmp600
photo of spectrometer psf600
photo of spectrometer sel600
photo of spectrometer fmp750
photo of spectrometer av300

fmp600

delivered in 1995, purchased with funds from the FMP
new hardware cabinet in 2012

Magnet

Bruker, unshielded, 52 mm bore

Hardware

AV III Console
sample changer (BACS-60)

Probes

5 mm QXI, z-gradient
5mm BBFO, z-Gradient
5 mm TXI, xyz-gradients
5 mm BBI, z-gradient
8 mm TXI, z-gradient

photo of spectrometer fmp600

psf600

delivered in 1999 as DRX, purchased with funds from the BMBF
upgraded to AV in 2010, cryoplattform replacement in 2011

Magnet

Bruker, shielded, 54 mm bore

Hardware

AV III Console
sample changer (BACS 60)

Probes

5 mm TXI, z-gradient
5 mm QCI Cryoprobe, z-gradient

photo of spectrometer psf600

sel600

delivered in 2008, purchased with funds from the FMP

Magnet

Bruker, shielded plus, 54 mm bore

Hardware

AV III Console
sample changer (BACS 60)

Probes

5 mm TCI Cryoprobe, z-grandient

photo of spectrometer sel600

fmp750

delivered in 1996 as a DMX, purchased with funds from the FMP
upgraded to AV in 2007

Magnet

Magnex, unshielded, 52 mm bore

Hardware

AV III Console

Probes

5 mm TXI, xyz-gradients
8 mm TXI, z-gradient
5 mm TCI Cryoprobe, z-grandient

photo of spectrometer fmp750

av300

delivered in 2005, purchased with funds from the FMP, new hardware cabinet in 2016

Magnet

Bruker, shielded, 54 mm bore

Hardware

AVIII Console
sample changer (BACS 120)

Probes

5 mm QNP (13C, 19F, 31P), z-gradient
5mm BBFO, z-Gradient

photo of spectrometer av300

dnp400

delivered in 2007, purchased with funds from the FMP, moved in 2008
upgraded with Gyrotron to enable DNP in 2009

Magnet

Bruker, shielded, 89 mm bore (switched to magnet from other 400 WB in 2008)

Hardware

AV III Console

Probes

2.5 mm MAS HXY
3.2 mm MAS HXY
3.2 mm MAS HXY (Low-T for DNP)
4.0 mm MAS HXY

av600

delivered in 2003, purchased with funds from the BMBF and the FMP

Magnet

Bruker, shielded, 89 mm bore

Hardware

AV III Console

Probes

1.3 mm MAS HXY
1.9 mm MAS HXY
3.2 mm MAS HXY
4.0 mm MAS HXY

av700

delivered in 2005, purchased with funds from the the FMP

Magnet

Bruker, shielded plus, 89 mm bore

Hardware

AV NEO Console

Probes

1.9 mm MAS HCND
3.2 mm MAS HXY
3.2 mm MAS HCN (Efree)
4.0 mm MAS HXY

av800

delivered in 2013, purchased with funds from the FMP upgraded with Gyrotron to enable DNP in 2019

Magnet

Bruker, shielded plus, 89 mm bore

Hardware

AV III Console

Probes

1.3 mm MAS HCND
1.9 mm MAS HXY (Low-T for DNP)
3.2 mm MAS HCN (Efree)
4.0 mm MAS HCN (Efree)

av900

delivered in 2004, purchased with funds from the BMBF and the city of Berlin

Magnet

Bruker, unshielded, 54 mm bore

Hardware

AV NEO Console

Probes

5 mm TXI, z-gradient
1.3 mm MAS (VTX) HCND
1.9 mm MAS HCND
3.2 mm MAS HCN
4.0 mm MAS HCN

photo dnp equipment
photo of spectrometer av600
photo of spectrometer av700
photo of spectrometer
photo of spectrometer av900

dnp400

delivered in 2007, purchased with funds from the FMP, moved in 2008
upgraded with Gyrotron to enable DNP in 2009

Magnet

Bruker, shielded, 89 mm bore (switched to magnet from other 400 WB in 2008)

Hardware

AV III Console

Probes

2.5 mm MAS HXY
3.2 mm MAS HXY
3.2 mm MAS HXY (Low-T for DNP)
4.0 mm MAS HXY

photo dnp equipment

av600

delivered in 2003, purchased with funds from the BMBF and the FMP

Magnet

Bruker, shielded, 89 mm bore

Hardware

AV III Console

Probes

1.3 mm MAS HXY
1.9 mm MAS HXY
3.2 mm MAS HXY
4.0 mm MAS HXY

photo of spectrometer av600

av700

delivered in 2005, purchased with funds from the the FMP

Magnet

Bruker, shielded plus, 89 mm bore

Hardware

AV NEO Console

Probes

1.9 mm MAS HCND
3.2 mm MAS HXY
3.2 mm MAS HCN (Efree)
4.0 mm MAS HXY

photo of spectrometer av700

av800

delivered in 2013, purchased with funds from the FMP upgraded with Gyrotron to enable DNP in 2019

Magnet

Bruker, shielded plus, 89 mm bore

Hardware

AV III Console

Probes

1.3 mm MAS HCND
1.9 mm MAS HXY (Low-T for DNP)
3.2 mm MAS HCN (Efree)
4.0 mm MAS HCN (Efree)

photo of spectrometer

av900

delivered in 2004, purchased with funds from the BMBF and the city of Berlin

Magnet

Bruker, unshielded, 54 mm bore

Hardware

AV NEO Console

Probes

5 mm TXI, z-gradient
1.3 mm MAS (VTX) HCND
1.9 mm MAS HCND
3.2 mm MAS HCN
4.0 mm MAS HCN

photo of spectrometer av900

Creative Commons License

This text and the images are published under the Creative Commons licence "CC BY-NC-ND 4.0 EN - Attribution-Non-Commercial-No Derivative Works 4.0 Germany". Author: Peter Schmieder for leibniz-fmp.de

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