The SSFA-GPHR information source

is a resource for Sequence- Structure- and Function- Analysis on a subgroup of G-protein-coupled receptors, the Glycoprotein Hormone Receptors (GPHR).

Data from studies on naturally occurring mutations and site-directed mutations are linked with 3D structures/structural models of these proteins.

The goal is to obtain new molecular insights into function and pathogenic malfunction of these pivotal proteins that are relevant in the thyroid  and gonadotroph.

SSFA-GPHR Database