Publications

Publications 2020

§, # equal contribution; * corresponding author(s); bold: FMP members

Alsalim, R., P. Lindemann, M. P. Lopez-Alberca, S. Miksche, W. Czechtizky, N. Halland*, M. Nazare*, A Palladium-Catalyzed Domino Reaction To Access 3-Amino-2H-indazoles from Hydrazines and 2-Halobenzonitriles. Org Lettonline ahead of print (2020). https://doi.org/10.1021/acs.orglett.0c02766

Barone, M., M. Müller, S. Chiha, J. Ren, D. Albat, A. Soicke, S. Dohmen, M. Klein, J. Bruns, M. van Dinther, R. Opitz, P. Lindemann, M. Beerbaum, K. Motzny, Y. Roske, P. Schmieder, R. Volkmer, M. Nazare, U. Heinemann, H. Oschkinat, P. Ten Dijke*, H. G. Schmalz*, R. Kühne*, Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells. Proc Natl Acad Sci USAonline ahead of print (2020). https://doi.org/10.1073/pnas.2007213117

Baumann, A. L., S. Schwagerus, K. Broi, K. Kemnitz-Hassanin, C. E. Stieger, N. Trieloff, P. Schmieder, C. P. R. Hackenberger*, Chemically Induced Vinylphosphonothiolate Electrophiles for Thiol-Thiol Bioconjugations. J Am Chem Soc142, 9544-9552 (2020). https://doi.org/10.1021/jacs.0c03426

Bertovic, I., R. Kurelic, I. Milosevic, M. Bender, M. Krauss, V. Haucke, A. Jurak Begonja*, Vps34 derived phosphatidylinositol 3-monophosphate modulates megakaryocyte maturation and proplatelet production through late endosomes/lysosomes. J Thromb Haemost18, 1756-1772 (2020). https://doi.org/10.1111/jth.14764

Braun*, B. C., N. Halaski, J. Painer, E. Krause, K. Jewgenow, The antioxidative enzyme SOD2 is important for physiological persistence of corpora lutea in lynxes. Sci Rep10, 3681 (2020). https://doi.org/10.1038/s41598-020-60634-x

Brennecke, B., Q. Wang, Q. Zhang, H. Y. Hu*, M. Nazaré*, An Activatable Lanthanide Luminescent Probe for Time-Gated Detection of Nitroreductase in Live Bacteria. Angew Chem Int Ed59, 8512-8516 (2020).  https://doi.org/10.1002/anie.202002391

Chilczuk, T., R. Monson, P. Schmieder, V. Christov, H. Enke, G. Salmond, T. H. J. Niedermeyer*, Ambigols from the Cyanobacterium Fischerella ambigua Increase Prodigiosin Production in Serratia spp. ACS Chem Biol15, 2929-2936 (2020). https://doi.org/10.1021/acschembio.0c00554

Chin, A. C., Z. Gao, A. M. Riley, D. Furkert, C. Wittwer, A. Dutta, T. Rojas, E. R. Semenza, R. A. Felder, J. L. Pluznick, H. J. Jessen, D. Fiedler, B. V. L. Potter, S. H. Snyder*, C. Fu*, The inositol pyrophosphate 5-InsP7 drives sodium-potassium pump degradation by relieving an autoinhibitory domain of PI3K p85alpha. Sci Adv6, eabb8542 (2020). https://doi.org/10.1126/sciadv.abb8542

Chow*, W. Y., B. P. Norman, N. B. Roberts, L. R. Ranganath, C. Teutloff, R. Bittl, M. J. Duer, J. A. Gallagher*, H. Oschkinat*, Pigmentation Chemistry and Radical-Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage. Angew Chem Int Ed59, 11937-11942 (2020). https://doi.org/10.1002/anie.202000618

Clochard, J., G. Jerz, P. Schmieder, H. Mitdank, M. Tröger, S. c. Sama, A. Weng, A new acetylated triterpene saponin from Agrostemma githago L. modulates gene delivery efficiently and shows a high cellular tolerance. Int J Pharmaceut589, 119822 (2020). https://doi.org/10.1016/j.ijpharm.2020.119822

D'Andrea, E. D., Y. Roske, G. A. P. de Oliveira, N. Cremer, A. Diehl, P. Schmieder, U. Heinemann, H. Oschkinat, J. R. Pires, Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi. J Struct Biol211, 107536 (2020). https://doi.org/10.1016/j.jsb.2020.107536

Dema, A., D. Faust, K. Lazarow, M. Wippich, M. Neuenschwander, K. Zühlke, A. Geelhaar, T. Pallien, E. Hallscheidt, J. Eichhorst, B. Wiesner, H. Cernecka, O. Popp, P. Mertins, G. Dittmar, J. P. von Kries, E. Klussmann, Cyclin-Dependent Kinase 18 Controls Trafficking of Aquaporin-2 and Its Abundance through Ubiquitin Ligase STUB1, Which Functions as an AKAP. Cells9, E673 (2020). https://doi.org/10.3390/cells9030673

Desmarini, D., S. Lev, D. Furkert, B. Crossett, A. Saiardi, K. Kaufman-Francis, C. Li, T. C. Sorrell, L. Wilkinson-White, J. Matthews, D. Fiedler, J. T. Djordjevic*, IP7-SPX Domain Interaction Controls Fungal Virulence by Stabilizing Phosphate Signaling Machinery. mBio11 (2020). https://doi.org/10.1128/mBio.01920-20

Dohmen, S., M. Reiher, D. Albat, S. Akyol, M. Barone, J. M. Neudorfl, R. Kühne, H. G. Schmalz*, Pd-Catalyzed Asymmetric N-Allylation of Amino Acid Esters with Exceptional Levels of Catalyst Control: Stereo-Divergent Synthesis of ProM-15 and Related Bicyclic Dipeptide Mimetics. Chemistry26, 3049-3053 (2020). https://doi.org/10.1002/chem.202000307

Ercu, M., L. Marko, C. Schächterle, D. Tsvetkov, Y. Cui, S. Maghsodi, T. U. P. Bartolomaeus, P. G. Maass, K. Zühlke, N. Gregersen, N. Hübner, R. Hodge, A. Mühl, B. Pohl, R. M. Illas, A. Geelhaar, S. Walter, H. Napieczynska, S. Schelenz, M. Taube, A. Heuser, Y. M. Anistan, F. Qadri, M. Todiras, R. Plehm, E. Popova, R. Langanki, J. Eichhorst, M. Lehmann, B. Wiesner, M. Russwurm, S. K. Forslund, I. Kamer, D. N. Müller, M. Gollasch, A. Aydin, S. Bähring, M. Bader, F. C. Luft, E. Klussmann, Phosphodiesterase 3A and Arterial Hypertension. Circulation142, 133-149 (2020). https://doi.org/10.1161/CIRCULATIONAHA.119.043061

Ernst, S., F. Ecker, M. S. Kaspers, P. Ochtrop, C. Hedberg, M. Groll, A. c. Itzen, Legionella effector AnkX displaces the switch II region for Rab1b phosphocholination. Sci Adv6, eaaz8041 (2020). https://doi.org/10.1126/sciadv.aaz8041

Fang, Z., S. Chen, Y. Manchanda, P. Bitsi, P. Pickford, A. David, M. M. Shchepinova, I. Corrêa Jr, D. J. Hodson, J. Broichhagen, E. W. Tate, F. Reimann, V. Salem, G. A. Rutter, T. Tan, S. R. Bloom, A. Tomas, B. J. Jones, Ligand-specific factors influencing GLP-1R post-endocytic trafficking and degradation. Int J Mol Sci, accepted (2020).

Fang, Z., S. Chen, P. Pickford, J. Broichhagen, D. J. Hodson, I. R. Correa, Jr., S. Kumar, F. Görlitz, C. Dunsby, P. M. W. French, G. A. Rutter, T. Tan, S. R. Bloom, A. Tomas, B. Jones, The Influence of Peptide Context on Signaling and Trafficking of Glucagon-like Peptide-1 Receptor Biased Agonists. ACS Pharmacol Transl Sci3, 345-360 (2020). https://doi.org/10.1021/acsptsci.0c00022

Finger, S., A. M. Kerth, M. Dathe, A. Blume, The impact of non-ideality of lipid mixing on peptide induced lipid clustering. Biochim Biophys Acta Biomembr1862, 183248 (2020). https://doi.org/10.1016/j.bbamem.2020.183248

Finkenwirth, F., M. Sippach, S. N. Pecina, M. Gade, J. Ruta, A. Ricke, E. Bondarenko, J. P. Klare, M. Zinke, S. Lange, A. Lange, H. J. Steinhoff, T. Eitinger, Dynamic interactions of CbiN and CbiM trigger activity of a cobalt energy-coupling-factor transporter. Biochim Biophys Acta Biomembr1862, 183114 (2020). https://doi.org/10.1016/j.bbamem.2019.183114

Friedrich, D., F. N. Brünig, A. J. Nieuwkoop, R. R. Netz, P. Hegemann, H. Oschkinat, Collective exchange processes reveal an active site proton cage in bacteriorhodopsin. Communications Biology3, 4 (2020). https://doi.org/10.1038/s42003-019-0733-7

Friedrich, D., J. Perodeau, A. J. Nieuwkoop*, H. Oschkinat*, MAS NMR detection of hydrogen bonds for protein secondary structure characterization. J Biomol NMR 74, 247-256 (2020). https://doi.org/10.1007/s10858-020-00307-z

Furkert, D., S. Hostachy, M. Nadler-Holly, D. Fiedler, Triplexed Affinity Reagents to Sample the Mammalian Inositol Pyrophosphate Interactome. Cell Chem Biol27, 1097-1108 (2020). https://doi.org/10.1016/j.chembiol.2020.07.017

Furkert, D., M. Nadler-Holly, D. Fiedler, Affinity-enrichment and identification of inositol poly- and pyrophosphate interactomes. STAR Methods in press,  (2020).

Gallrein§, C., M. Iburg§, T. Michelberger, A. Kocak, D. Puchkov, F. Liu, S. M. Ayala Mariscal, T. Nayak, G. S. Kaminski Schierle, J. Kirstein, Novel Amyloid-beta pathology C. elegans model reveals distinct neurons as seeds of pathogenicity. Prog NeurobiolOnline ahead of print, 101907 (2020). https://doi.org/10.1016/j.pneurobio.2020.101907

Gericke, B., K. Römermann, A. f. Noack, S. Noack, J. Kronenberg, I. E. Blasig*, W. Löscher*, A face-to-face comparison of claudin-5 transduced human brain endothelial (hCMEC/D3) cells with porcine brain endothelial cells as blood-brain barrier models for drug transport studies. Fluids and barriers of the CNS17, 53 (2020). https://doi.org/10.1186/s12987-020-00212-5

Gerland*, L., D. Friedrich, L. Hopf, E. J. Donovan, A. Wallmann, N. Erdmann, A. Diehl, M. Bommer, K. Buzar, M. Ibrahim, P. Schmieder, H. Dobbek, A. Zouni, A. N. Bondar, H. Dau, H. Oschkinat*, pH-Dependent Protonation of Surface Carboxylate Groups in PsbO Enables Local Buffering and Triggers Structural Changes. ChemBioChem21, 1597-1604 (2020). https://doi.org/10.1002/cbic.201900739

Gonschior, H., V. Haucke, M. Lehmann, Super-Resolution Imaging of Tight and Adherens Junctions: Challenges and Open Questions. Int J Mol Sci21, 544 (2020). Review, https://doi.org/10.3390/ijms21030744

Gonzalez-Lozano, M. A., F. Koopmans, P. F. Sullivan, J. Protze, G. Krause, M. Verhage, K. W. Li*, F. Liu#*, A. B. Smit#*, Stitching the synapse: Cross-linking mass spectrometry into resolving synaptic protein interactions. Sci Adv6, eaax5783 (2020). https://doi.org/10.1126/sciadv.aax5783

Göppner, C., A. H. Soria, M. B. Hoegg-Beiler, T. J. Jentsch, Cellular basis of ClC-2 Cl- channel-related brain and testis pathologies. J Biol Chemin press  (2020). https://doi.org/10.1074/jbc.RA120.016031

Gowrisankaran, S., S. Houy, J. G. P. del Castillo, V. Steubler, M. Gelker, J. Kroll, P. S. Pinheiro, D. Schwitters, N. Halbsgut, A. Pechstein, J. R. T. van Weering, T. Maritzen, V. Haucke, N. Raimundo, J. B. Sorensen, I. Milosevic, Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin. Nat Commun11, 1266 (2020). https://doi.org/10.1038/s41467-020-14993-8

Hackenberger, C. P. R., P. E. Dawson, Y. X. Chen, H. Hojo, Modern Peptide and Protein Chemistry: Reaching New Heights. J Org Chem85, 1328-1330 (2020). Editorial, https://doi.org/10.1021/acs.joc.0c00104

Haenig, C., N. Atias, A. K. Taylor, A. Mazza, M. H. Schaefer, J. Russ, S. P. Riechers, S. Jain, M. Coughlin, J. F. Fontaine, B. D. Freibaum, L. Brusendorf, M. Zenkner, P. Porras, M. Stroedicke, S. Schnoegl, K. Arnsburg, A. Boeddrich, L. Pigazzini, P. Heutink, J. P. Taylor, J. Kirstein, M. A. Andrade-Navarro, R. Sharan, E. E. Wanker, Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains. Cell Rep32, 108050 (2020). https://doi.org/10.1016/j.celrep.2020.108050

Hauser, A., S. Hwang, H. Sun*, C. P. R. Hackenberger*, Combining free energy calculations with tailored enzyme activity assays to elucidate substrate binding of a phospho-lysine phosphatase. Chem Sci (2020). https://doi.org/10.1039/D0SC03930F

Hauser, A., E. Poulou, F. Müller, P. Schmieder, C. P. R. Hackenberger, Synthesis and evaluation of non-hydrolyzable phospho-lysine peptide mimics. ChemistryOnline ahead of print,  (2020). https://doi.org/10.1002/chem.202003947

Hecht-Höger, A. M., B. C. Braun, E. Krause, A. Meschede, R. Krahe, C. C. Voigt, A. D. Greenwood, G. A. Czirjak, Plasma proteomic profiles differ between European and North American myotid bats colonized by Pseudogymnoascus destructans. Mol Ecol 29, 1745-1755 (2020). https://doi.org/10.1111/mec.15437

Heidenreich, S., P. Weber, H. Stephanowitz, K. M. Petricek, T. Schütte, M. Oster, A. M. Salo, M. Knauer, I. Goehring, N. Yang, N. Witte, A. Schumann, M. Sommerfeld, M. Muenzner, J. Myllyharju, E. Krause, M. Schupp, The glucose-sensing transcription factor ChREBP is targeted by proline hydroxylation. J Biol Chem295, 17158-17168 (2020). https://doi.org/10.1074/jbc.RA120.014402

Hempel, C., J. Protze, E. Altun, B. Riebe , A. Piontek, A. Fromm , I. M. Lee, T. Saleh, D. Günzel, G. Krause, J. Piontek*, Assembly of Tight Junction Strands: Claudin-10b and Claudin-3 Form Homo-Tetrameric Building Blocks that Polymerise in a Channel-Independent Manner. J Mol Biol432, 2405-2427 (2020). https://doi.org/10.1016/j.jmb.2020.02.034

Hoffmann, J., J. Ruta, C. Shi, K. Hendriks, V. Chevelkov, W. T. Franks, H. Oschkinat, K. Giller, S. Becker, A. Lange, Protein resonance assignment by BSH-CP based 3D solid-state NMR experiments: A practical guide. Magn Reson Chem58, 445-465 (2020). https://doi.org/10.1002/mrc.4945

Iburg, M., D. Puchkov, I. U. Rosas-Brugada, L. Bergemann, U. Rieprecht, J. Kirstein, The noncanonical small heat shock protein HSP-17 from Caenorhabditis elegans is a selective protein aggregase. J Biol Chem295, 3064-3079 (2020). https://doi.org/10.1074/jbc.RA119.011185

Jäpel, M., F. Gerth, T. Sakaba, J. Bacetic, L. J. Yao, S. J. Koo, T. Maritzen, C. Freund, V. Haucke, Intersectin-Mediated Clearance of SNARE Complexes Is Required for Fast Neurotransmission. Cell Rep30, 409-420 (2020). https://doi.org/10.1016/j.celrep.2019.12.035

Jayapaul, J., L. Schröder, Probing Reversible Guest Binding with Hyperpolarized (129)Xe-NMR: Characteristics and Applications for Cucurbit[n]urils. Molecules25, 957 (2020). Review, https://doi.org/10.3390/molecules25040957

Jayapaul, J., L. Schröder, Molecular Sensing with Host Systems for Hyperpolarized (129)Xe. Molecules25, 4627 (2020). Review, https://doi.org/10.3390/molecules25204627

Kasper*, M. A., M. Gerlach, A. F. L. Schneider, C. Groneberg, P. Ochtrop, S. Boldt, D. Schumacher, J. Helma, H. Leonhardt, M. Christmann, C. P. R. Hackenberger*, N-Hydroxysuccinimide-Modified Ethynylphosphonamidates Enable the Synthesis of Configurationally Defined Protein Conjugates. ChemBioChem21, 113-119 (2020). https://doi.org/10.1002/cbic.201900587

Kircher, T., T. Pantsar, A. Oder, J. P. von Kries, M. Juchum, B. Pfaffenrot, P. Kloevekorn, W. Albrecht, R. Selig, S. Laufer, Design and synthesis of novel fluorescently labeled analogs of vemurafenib targeting MKK4. Eur J Med ChemOnline ahead of print, 112901 (2020). https://doi.org/10.1016/j.ejmech.2020.112901

Kobbersmed, J. R. L., A. T. Grasskamp, M. Jusyte, M. A. Böhme, S. Ditlevsen, J. B. Sorensen*, A. M. Walter*, Rapid regulation of vesicle priming explains synaptic facilitation despite heterogeneous vesicle:Ca(2+) channel distances. Elife9, e51032 (2020). https://doi.org/10.7554/eLife.51032

Kohn, J. M., J. Riedel, J. Horsch, H. Stephanowitz, H. G. Börner, Mussel-Inspired Polymerization of Peptides: The Chemical Activation Route as Key to Broaden the Sequential Space of Artificial Mussel-Glue Proteins. Macromol Rapid Comm41, e1900431 (2020). https://doi.org/10.1002/marc.201900431

Krause*, G., K. M. Hinz, Molecular Mechanisms of Thyroid Hormone Transport by l-Type Amino Acid Transporter. Exp Clin Endocrinol Diab128, 379-382 (2020). Review, https://doi.org/10.1055/a-1032-8369

Kroll, J., O. D. Özcete, S. Jung, T. Maritzen, I. Milosevic, C. Wichmann, T. Moser, AP180 promotes release site clearance and clathrin-dependent vesicle reformation in mouse cochlear inner hair cells. J Cell Sci133, jcs236737 (2020). https://doi.org/10.1242/jcs.236737

Kuijpers, M., G. Kochlamazashvili, A. Stumpf, D. Puchkov, A. Swaminathan, M. T. Lucht, E. Krause, T. Maritzen, D. Schmitz, V. Haucke, Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum. Neuron109, 1-15 (2020). https://doi.org/10.1016/j.neuron.2020.10.005

Kunth, M., L. Schröder*, Binding Site Exchange Kinetics Revealed Through Efficient Spin-Spin Dephasing of Hyperpolarized 129Xe. Chem Sciin print,  (2020). https://doi.org/10.1039/d0sc04835f

Kutle, I., K. M. Szymanska-de Wijs, B. Bogdanow, B. Cuvalo, L. Steinbrück, S. Jonjic, K. Wagner, R. Niedenthal, M. Selbach, L. Wiebusch, M. Dezeljin, M. Messerle, Murine cytomegalovirus M25 proteins sequester the tumor suppressor protein p53 in nuclear accumulations. J VirolOnline ahead of print,  (2020). https://doi.org/10.1128/JVI.00574-20

Laezer, I., S. E. Palma-Vera, F. Liu, M. Frank, N. Trakooljul, A. Vernunft, J. Schoen, S. Chen, Dynamic profile of EVs in porcine oviductal fluid during the periovulatory period. Reproduction159, 371-382 (2020). https://doi.org/10.1530/Rep-19-0219

Lämmle, C. A., A. Varady, T. G. Müller, C. Sturtzel, M. Riepl, B. Mathes, J. Eichhorst, A. Sporbert, M. Lehmann, H. G. Kräusslich, M. Distel, J. Broichhagen, Photocaged Hoechst Enables Subnuclear Visualization and Cell Selective Staining of DNA in vivo. ChemBioChem21, 1-10 (2020). https://doi.org/10.1002/cbic.202000465

Lauster§, D., S. Klenk§, K. Ludwig, S. Nojoumi, S. Behren, L. Adam, M. Stadtmüller, S. Saenger, S. Zimmler, K. Honzke, L. Yao, U. Hoffmann, M. Bardua, A. Hamann, M. Witzenrath, L. E. Sander, T. Wolff, A. C. Hocke, S. Hippenstiel, S. De Carlo, J. Neudecker, K. Osterrieder, N. Budisa, R. R. Netz, C. Böttcher, S. Liese*, A. Herrmann*, C. P. R. Hackenberger*, Phage capsid nanoparticles with defined ligand arrangement block influenza virus entry. Nat Nanotechnol15, 373-379 (2020). https://doi.org/10.1038/s41565-020-0660-2

Leippe§, P., J. Broichhagen§, K. Cailliau, A. Mougel, M. Morel, C. Dissous, D. Trauner, J. Vicogne, Transformation of Receptor Tyrosine Kinases into Glutamate Receptors and Photoreceptors. Angew Chem Int Ed59, 6720-6723 (2020). Communications, https://doi.org/10.1002/anie.201915352

Li, M., R. Puschmann, A. Herdlitschka, D. Fiedler, H. Wennemers, Delivery ofmyo-Inositol Hexakisphosphate to the Cell Nucleus with a Proline-Based Cell-Penetrating Peptide. Angew Chem Int Ed59, 15586-15589 (2020). https://doi.org/10.1002/anie.202006770

Li, X. Y., C. F. Gu, S. Hostachy, S. Sahu, C. Wittwer, H. J. Jessen, D. Fiedler, H. C. Wang, S. B. Shears, Control of XPR1-dependent cellular phosphate efflux by InsP(8) is an exemplar for functionally-exclusive inositol pyrophosphate signaling. Proc. Natl. Acad. Sci. U.S.A. 117, 3568-3574 (2020). https://doi.org/10.1073/pnas.1908830117

Li§, X. L., L. P. Chi§, A. Navarro-Vazquez, S. Hwang, P. Schmieder, X. M. Li, X. Li, S. Q. Yang, X. X. Lei*, B. G. Wang*, H. Sun*, Stereochemical Elucidation of Natural Products from Residual Chemical Shift Anisotropies in a Liquid Crystalline Phase. J Am Chem Soc142, 2301-2309 (2020). https://doi.org/10.1021/jacs.9b10961

Liu, H., P. Chen, X. L. Li, H. Sun, X. X. Lei*, Practical aspects of oligopeptide AAKLVFF as an alignment medium for the measurements of residual dipolar coupling of organic molecules. Magn Reson Chem58, 404-410 (2020). https://doi.org/10.1002/mrc.4825

Liu, H., M. N. Paddock, H. Wang, C. J. Murphy, R. C. Geck, A. J. Navarro, G. M. Wulf, O. Elemento, V. Haucke, L. C. Cantley, A. Toker, The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple Negative Breast Cancer. Cancer Discovery10, 1226-1239 (2020). doi.org/10.1158/2159-8290

Lopez-Hernandez*, T., T. Maritzen*, V. Haucke*, Ramping up the autophagy-lysosome system to cope with osmotic stress. Autophagy16, 1921-1922 (2020). https://doi.org/10.1080/15548627.2020.1798065

Lopez-Hernandez*, T., D. Puchkov, E. Krause, T. Maritzen*, V. Haucke*, Endocytic regulation of cellular ion homeostasis controls lysosome biogenesis. Nat Cell Biol22, 815-827 (2020). https://doi.org/10.1038/s41556-020-0535-7

Maaßen, A., J. M. Gebauer, E. T. Abraham, I. Grimm, J. M. Neudorfl, R. Kühne, I. Neundorf, U. Baumann, H. G. Schmalz, Triple-Helix-Stabilizing Effects in Collagen Model Peptides Containing PPII-Helix-Preorganized Diproline Modules. Angew Chem Int Ed59, 5747-5755 (2020). https://doi.org/10.1002/anie.201914101

Matthaeus, C., I. Lahmann, S. Kunz, W. Jonas, A. A. Melo, M. Lehmann, E. Larsson, R. Lundmark, M. Kern, M. Bluher, H. Olschowski, J. Kompa, B. Brügger, D. N. Müller, V. Haucke, A. Schürmann, C. Birchmeier, O. Daumke, EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake. Proc Natl Acad Sci USA117, 7471-7481 (2020). doi.org/10.1073/pnas.1918415117

Morrison, E., T. Wegner, A. E. Zucchetti, M. Alvaro-Benito, A. Zheng, S. Kliche, E. Krause, B. Brugger, C. Hivroz, C. Freund, Dynamic palmitoylation events following T-cell receptor signaling. Communications Biology 3, 368 (2020). https://doi.org/10.1038/s42003-020-1063-5

Mostinski, Y., G. Heynen, M. P. Lopez-Alberca, J. Paul, S. Miksche, S. Radetzki, D. Schaller, E. Shanina, C. Seyffarth, Y. Kolomeets, N. Ziebart, J. de Schryver, S. Oestreich, M. Neuenschwander, Y. Roske, U. Heinemann, C. Rademacher, A. Volkamer, J. P. von Kries, W. Birchmeier, M. Nazare, From Pyrazolones to Azaindoles: Evolution of Active-Site SHP2 Inhibitors Based on Scaffold Hopping and Bioisosteric Replacement. J Med Chem Online ahead of print,  (2020). https://doi.org/10.1021/acs.jmedchem.0c01265

Nakamura, R., T. Numata, G. Kasuya*, T. Yokoyama, T. Nishizawa, T. Kusakizako, T. Kato, T. Hagino, N. Dohmae, M. Inoue, K. Watanabe, H. Ichijo, M. Kikkawa, M. Shirouzu, T. J. Jentsch, R. Ishitani, Y. Okada, O. Nureki, Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation. Commun Biol3, 240 (2020). https://doi.org/10.1038/s42003-020-0951-z

Nematian-Ardestani, E., F. Abd-Wahab, F. C. Chatelain, H. Sun, M. Schewe, T. Baukrowitz, S. J. Tucker, Selectivity filter instability dominates the low intrinsic activity of the TWIK-1 K2P K+ channel. J Biol Chem295, 610-618 (2020). https://doi.org/10.1074/jbc.RA119.010612

Ochtrop, P., C. P. R. Hackenberger, Recent advances of thiol-selective bioconjugation reactions. Curr Opin Chem Biol58, 28-36 (2020). Review, https://doi.org/10.1016/j.cbpa.2020.04.017

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