Publications

Publications 2019

§, # equal contribution; * corresponding author(s); bold: FMP members

Alex, A., V. Piano, S. Polley, M. Stuiver, S. Voss, G. Ciossani, K. Overlack, B. Voss, S. Wohlgemuth, A. Petrovic, Y. Wu, P. Selenko, A. Musacchio*, S. Maffini*, Electroporated recombinant proteins as tools for in vivo functional complementation, imaging and chemical biology. Elife8, e48287 (2019). https://doi.org/10.7554/eLife.48287

Apel§, C., M. A. Kasper§*, C. E. Stieger, C. P. R. Hackenberger*, M. Christmann*, Protein Modification of Lysine with 2-(2-Styrylcyclopropyl)ethanal. Org Lett21, 10043-10047 (2019). https://doi.org/10.1021/acs.orglett.9b03982

Arrey, F., D. Löwe, S. Kuhlmann, P. Kaiser, P. Moura-Alves, G. Krishnamoorthy, L. Lozza, J. Maertzdorf, T. Skrahina, A. Skrahina, M. Gengenbacher, G. Nouailles*, S. H. E. Kaufmann, Humanized Mouse Model Mimicking Pathology of Human Tuberculosis for in vivo Evaluation of Drug Regimens. Front Immunol10, 89 (2019). doi.org/10.3389/fimmu.2019.00089

Artarini, A., M. Meyer, Y. J. Shin, K. Huber, N. Hilz, F. Bracher, D. Eros, L. Orfi, G. Keri, S. Goedert, M. Neuenschwander, J. von Kries, Y. Domovich-Eisenberg, N. Dekel, I. Szabadkai, M. Lebendiker, Z. Horvath, T. Danielie, O. Livnahe, O. Moncorge, R. Frise, W. Barclay, T. F. Meyer, A. Karlas, Regulation of influenza A virus mRNA splicing by CLK1. Antivir Res168, 187-196 (2019). https://doi.org/10.1016/j.antiviral.2019.06.003

Ayala, S., P. Genevaux, C. Hureau, P. Faller, (Bio)chemical Strategies To Modulate Amyloid-beta Self-Assembly. ACS Chem Neurosci10, 3366-3374 (2019). Review, https://doi.org/10.1021/acschemneuro.9b00239

Azarnia Tehran§, D., T. Lopez-Hernandez§, T. Maritzen, Endocytic Adaptor Proteins in Health and Disease: Lessons from Model Organisms and Human Mutations. Cells8, 1345 (2019). Review, https://doi.org/134510.3390/cells8111345

Baumann, A. L., C. P. R. Hackenberger, Tag and release: strategies for the intracellular cleavage of protein conjugates. Curr Opin Chem Biol52, 39-46 (2019). Review, https://doi.org/10.1016/j.cbpa.2019.04.019

Beier, L. S., J. Rossa, S. Woodhouse, S. Bergmann, H. B. Kramer, J. Protze, M. Eichner, A. Piontek, S. Vidal-y-Sy, J. M. Brandner, G. Krause, N. Zitzmann, J. Piontek, Use of Modified Clostridium perfringens Enterotoxin Fragments for Claudin Targeting in Liver and Skin Cells. Int J Mol Sci20, 4774 (2019). https://doi.org/10.3390/ijms20194774

Berndt, P., L. Winkler*, J. Cording, O. Breitkreuz-Korff, A. Rex, S. Dithmer, V. Rausch, R. Blasig, M. Richter, A. Sporbert, H. Wolburg, I. E. Blasig, R. F. Haseloff*, Tight junction proteins at the blood-brain barrier: far more than claudin-5. Cell Mol Life Sci76, 1987-2002 (2019). https://doi.org/10.1007/s00018-019-03030-7

Bhukel, A., C. B. Beuschel, M. Maglione, M. Lehmann, G. Juhasz, F. Madeo, S. J. Sigrist, Autophagy within the mushroom body protects from synapse aging in a non-cell autonomous manner. Nat Commun10, 1318 (2019). doi.org/10.1038/s41467-019-09262-2

Binger, K. J., M. Neukam, S. G. Tattikota, F. Qadri, D. Puchkov, D. M. Willmes, S. Wurmsee, S. Geisberger, R. Dechend, K. Raile, T. Kurth, G. Nguyen, M. N. Poy, M. Solimena, D. N. Müller, A. L. Birkenfeld, Atp6ap2 deletion causes extensive vacuolation that consumes the insulin content of pancreatic beta cells. Proc Natl Acad Sci USA116, 19983-19988 (2019). https://doi.org/10.1073/pnas.1903678116

Birke, R., E. Krause, M. Schümann, I. E. Blasig, R. F. Haseloff, Quantitative Evaluation of Different Protein Fractions of Cerebrospinal Fluid Using (18)O Labeling. Methods Mol Biol2044, 119-128 (2019). Book Chapter, https://doi.org/10.1007/978-1-4939-9706-0_8

Bogdanow, B., X. Wang, K. Eichelbaum, A. Sadewasser, I. Husic, K. Paki, M. Budt, M. Hergeselle, B. Vetter, J. Hou, W. Chen, L. Wiebusch, I. M. Meyer, T. Wolff, M. Selbach, The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant. Nat Commun10, 5518 (2019). https://doi.org/10.1038/s41467-019-13520-8

Böhme§, M. A., A. W. McCarthy§, A. T. Grasskamp, C. B. Beuschel, P. Goel, M. Jusyte, D. Laber, S. Huang, U. Rey, A. G. Petzoldt, M. Lehmann, F. Gottfert, P. Haghighi, S. W. Hell, D. Owald, D. Dickman, S. J. Sigrist*, A. M. Walter*, Rapid active zone remodeling consolidates presynaptic potentiation. Nat Commun10, 1085 (2019). https://doi.org/10.1038/s41467-019-08977-6

Brennecke, P., D. Rasina, O. Aubi, K. Herzog, J. Landskron, B. Cautain, F. Vicente, J. Quintana, J. Mestres, B. Stechmann, B. Ellinger, J. Brea, J. L. Kolanowski, R. Pilarski, M. Orzaez, A. Pineda-Lucena, L. Laraia, F. Nami, P. Zielenkiewicz, K. Paruch, E. Hansen, J. P. von Kries, M. Neuenschwander, E. Specker, P. Bartunek, S. Simova, Z. Lesnikowski, S. Krauss, L. Lehtio, U. Bilitewski, M. Bronstrup, K. Tasken, A. Jirgensons, H. Lickert, M. H. Clausen, J. H. Andersen, M. J. Vicent, O. Genilloud, A. Martinez, M. Nazaré, W. Fecke*, P. Gribbon*, EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology. Slas Discov24, 398-413 (2019). https://doi.org/10.1177/2472555218816276

Brinson, R. G., J. P. Marino, F. Delaglio, L. W. Arbogast, R. M. Evans, A. Kearsley, G. Gingras, H. Ghasriani, Y. Aubin, G. K. Pierens, X. Y. Jia, M. Mobli, H. G. Grant, D. W. Keizer, K. Schweimer, J. Stahle, G. Widmalm, E. R. Zartler, C. W. Lawrence, P. N. Reardon, J. R. Cort, P. Xu, F. Ni, S. Yanaka, K. Kato, S. R. Parnham, D. Tsao, A. Blomgren, T. Rundlof, N. Trieloff, P. Schmieder, A. Ross, K. Skidmore, K. Chen , D. Keire, D. I. Freedberg, T. Suter-Stahel, G. Wider, G. Ilc, J. Plavec, S. A. Bradley, D. M. Baldisseri, M. L. Sforca, A. C. D. Zeri, J. Y. Wei, C. M. Szabo, C. A. Amezcua, J. B. Jordan, M. Wikstrom, Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics. Mabs-Austin11, 94-105 (2019). https://doi.org/10.1080/19420862.2018.1544454

Brockmann§, M. M., M. Maglione§, C. G. Willmes§, A. Stumpf, B. A. Bouazza, L. M. Velasquez, M. K. Gräuel, P. Beed, M. Lehmann, N. Gimber, J. Schmoranzer, S. J. Sigrist, C. Rosenmund, D. Schmitz, RIM-BP2 primes synaptic vesicles via recruitment of Munc13-1 at hippocampal mossy fiber synapses. Elife8, e43243 (2019). https://doi.org/10.7554/eLife.43243

Buntz, A., T. Killian, D. Schmid, H. Seul, U. Brinkmann, J. Ravn, M. Lindholm, H. Knoetgen, V. Haucke, O. Mundigl, Quantitative fluorescence imaging determines the absolute number of locked nucleic acid oligonucleotides needed for suppression of target gene expression. Nucleic Acids Res47, 953-969 (2019). https://doi.org/10.1093/nar/gky1158

Castillo, X., S. Castro-Obregon, B. Gutierrez-Becker, G. Gutierrez-Ospina, N. Karalis, A. A. Khalil, J. S. Lopez-Noguerola, L. L. Rodriguez, E. Martinez-Martinez, C. Perez-Cruz, J. Perez-Velazquez, M. L. Pina, K. Rubio, H. P. S. Salazar Garcia, T. Syeda, A. Vanoye-Carlo, A. Villringeruo, K. Winek, M. Zille, Re-thinking the Etiological Framework of Neurodegeneration. Front Neurosci-Switz13, 728 (2019). Review, doi.org/10.3389/fnins.2019.00728

Chow, W. Y., Investigation of Triple-Helix Collagen Hydroxylation by Solid-State NMR Spectroscopy. Methods Mol Biol1944, 57-77 (2019). Book Chapter, doi.org/10.1007/978-1-4939-9095-5_5

Culemann, S., A. Grüneboom, J. A. Nicolas-Avila, D. Weidner, K. F. Lämmle, T. Rothe, J. A. Quintana, P. Kirchner, B. Krljanac, M. Eberhardt, F. Ferrazzi, E. Kretzschmar, M. Schicht, K. Fischer, K. Gelse, M. Faas, R. Pfeifle, J. A. Ackermann, M. Pachowsky, N. Renner, D. Simon, R. F. Haseloff, A. B. Ekici, T. Bäuerle, I. E. Blasig, J. Vera, D. Voehringer, A. Kleyer, F. Paulsen, G. Schett, A. Hidalgo, G. Krönke, Locally renewing resident synovial macrophages provide a protective barrier for the joint. Nature572, 670-675 (2019). https://doi.org/10.1038/s41586-019-1471-1

Dejonghe, W., I. Sharma, B. Denoo, S. De Munck, Q. Lu, K. Mishev, H. Bulut, E. Mylle, R. De Rycke, M. Vasileva, D. V. Savatin, W. Nerinckx, A. Staes, A. Drozdzecki, D. Audenaert, K. Yperman, A. Madder, J. Friml, D. Van Damme, K. Gevaert, V. Haucke, S. N. Savvides, J. Winne, E. Russinova, Disruption of endocytosis through chemical inhibition of clathrin heavy chain function. Nat Chem Biol15, 641-649 (2019). https://doi.org/10.1038/s41589-019-0262-1

Driller, R., M. Ballaschk, P. Schmieder, B. Uchanska-Ziegler, A. Ziegler*, B. Loll*, Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype. J Biol Chem294, 13269-13279 (2019). https://doi.org/10.1074/jbc.RA119.008937

Driller, J. H., J. Lutzkendorf, H. Depner, M. Siebert, B. Kuropka, C. Weise, C. Piao, A. G. Petzoldt, M. Lehmann, U. Stelzl, R. Zahedi, A. Sickmann, C. Freund, S. J. Sigrist, M. C. Wahl, Phosphorylation of the Bruchpilot N-terminus in Drosophila unlocks axonal transport of active zone building blocks. J Cell Sci132, jcs225151 (2019). https://doi.org/10.1242/jcs.225151

Ebner, M., P. A. Koch, V. Haucke, Phosphoinositides in the control of lysosome function and homeostasis. Biochem Soc T47, 1173-1185 (2019). Review, https://doi.org/10.1042/Bst20190158

Feleciano, D. R., K. Juenemann, M. Iburg, I. C. Bras, C. I. Holmberg, J. Kirstein, Crosstalk Between Chaperone-Mediated Protein Disaggregation and Proteolytic Pathways in Aging and Disease. Front Aging Neurosci11, 9 (2019). https://doi.org/10.3389/fnagi.2019.00009

Fred, S. M., L. Laukkanen, C. A. Brunello, L. Vesa, H. Goos, I. Cardon, R. Moliner, T. Maritzen, M. Varjosalo, P. C. Casarotto*, E. Castren, Pharmacologically diverse antidepressants facilitate TRKB receptor activation by disrupting its interaction with the endocytic adaptor complex AP-2. J Biol Chem294, 18150-18161 (2019). https://doi.org/10.1074/jbc.RA119.008837

Gerlach, M., T. Stoschek, H. Leonhardt, C. P. R. Hackenberger, D. Schumacher, J. Helma, Tubulin Tyrosine Ligase-Mediated Modification of Proteins. Methods Mol Biol2012, 327-355 (2019). Book Chapter, https://doi.org/10.1007/978-1-4939-9546-2_17

Gerth, F., M. Jäpel, J. Sticht, B. Kuropka, X. J. Schmitt, J. H. Driller, B. Loll, M. C. Wahl, K. Pagel, V. Haucke, C. Freund, Exon Inclusion Modulates Conformational Plasticity and Autoinhibition of the Intersectin 1 SH3A Domain. Structure27, 977-987 (2019). https://doi.org/10.1016/j.str.2019.03.020

Goel, P., D. D. Bergeron, M. A. Böhme, L. Nunnelly, M. Lehmann, C. Buser, A. M. Walter, S. J. Sigrist, D. Dickman, Homeostatic scaling of active zone scaffolds maintains global synaptic strength. J Cell Biol218, 1706-1724 (2019). https://doi.org/10.1083/jcb.201807165

Gohlke, S., V. Zagoriy, A. C. Inostroza, M. Meret, C. Mancini, L. Japtok, F. Schumacher, D. Kuhlow, A. Graja, H. Stephanowitz, M. Jahnert, E. Krause, A. Wernitz, K. J. Petzke, A. Schürmann, B. Kleuser, T. J. Schulz, Identification of functional lipid metabolism biomarkers of brown adipose tissue aging. Mol Metab24, 1-17 (2019). https://doi.org/10.1016/j.molmet.2019.03.011

Goldberga, I., R. Li, W. Y. Chow, D. G. Reid, U. Bashtanova, R. Rajan, A. Puszkarska, H. Oschkinat*, M. J. Duer*, Detection of nucleic acids and other low abundance components in native bone and osteosarcoma extracellular matrix by isotope enrichment and DNP-enhanced NMR. Rsc Adv9, 26686-26690 (2019). https://doi.org/10.1039/c9ra03198g

Göppner§, C., I. J. Orozco§, M. B. Hoegg-Beiler, A. H. Soria, C. A. Hübner, F. L. Fernandes-Rosa, S. Boulkroun, M. C. Zennaro, T. J. Jentsch, Pathogenesis of hypertension in a mouse model for human CLCN2 related hyperaldosteronism. Nat Commun10, 4678 (2019). https://doi.org/10.1038/s41467-019-12113-9

Gupta, R., H. L. Zhang, M. M. Lu, G. J. Hou, M. Caporini, M. Rosay, W. Maas, J. Struppe, J. Ahn, I. J. L. Byeon, H. Oschkinat, K. Jaudzems, E. Barbet-Massin, L. Emsley, G. Pintacuda*, A. Lesage*, A. M. Gronenborn*, T. Polenova*, Dynamic Nuclear Polarization Magic-Angle Spinning Nuclear Magnetic Resonance Combined with Molecular Dynamics Simulations Permits Detection of Order and Disorder in Viral Assemblies. J Phys Chem B123, 5048-5058 (2019). https://doi.org/10.1021/acs.jpcb.9b02293

Harmel§, R. K., R. Puschmann§, M. N. Trung, A. Saiardi, P. Schmieder, D. Fiedler, Harnessing C-13-labeled myo-inositol to interrogate inositol phosphate messengers by NMR. Chem Sci10, 5267-5274 (2019). https://doi.org/10.1039/c9sc00151d

Helbig§, I., T. Lopez-Hernandez§, O. Shor§, P. Galer, S. Ganesan, M. Pendziwiat, A. Rademacher, C. A. Ellis, N. Humpfer, N. Schwarz, S. Seiffert, J. Peeden, J. Shen, K. Sterbova, T. B. Hammer, R. S. Moller, D. N. Shinde, S. Tang, L. Smith, A. Poduri, R. Krause, F. Benninger#, K. L. Helbig#, V. Haucke#, Y. G. Weber*#, EuroEPINOMICS-RES Consortium, GRIN Consortium, A Recurrent Missense Variant in AP2M1 Impairs Clathrin-Mediated Endocytosis and Causes Developmental and Epileptic Encephalopathy. Am J Hum Genet104, 1060-1072 (2019). https://doi.org/10.1016/j.ajhg.2019.04.001

Höfer, C. T., S. Di Lella, I. Dahmani, N. Jungnick, N. Bordag, S. Bobone, Q. Huang, S. Keller, A. Herrmann, S. Chiantia, Structural determinants of the interaction between influenza A virus matrix protein M1 and lipid membranes. Biochim Biophys Acta Biomembr1861, 1123-1134 (2019). https://doi.org/10.1016/j.bbamem.2019.03.013

Horsch, J., P. Wilke, H. Stephanowitz, E. Krause, H. G. Börner, Fish and Clips: A Convenient Strategy to Identify Tyrosinase Substrates with Rapid Activation Behavior for Materials Science Applications. ACS Macro Lett8, 724-729 (2019). https://doi.org/10.1021/acsmacrolett.9b00244

Hwang, S., P. Fricke, M. Zinke, K. Giller, J. S. Wall, D. Riedel, S. Becker, A. Lange, Comparison of the 3D structures of mouse and human alpha-synuclein fibrils by it solid-state NMR and STEM. J Struct Biol206, 43-48 (2019). https://doi.org/10.1016/j.jsb.2018.04.003

Hwang, S., C. Öster, V. Chevelkov, K. Giller, S. Lange, S. Becker, A. Lange, Characterization of H/D exchange in type 1 pili by proton-detected solid-state NMR and molecular dynamics simulations. J Biomol NMR73, 281-291 (2019). https://doi.org/10.1007/s10858-019-00247-3

Iacobucci, C., C. Piotrowski, R. Aebersold, B. C. Amaral, P. Andrews, K. Bernfur, C. Borchers, N. I. Brodie, J. E. Bruce, Y. Cao, S. Chaignepain, J. D. Chavez, S. Claverol, J. Cox, T. Davis, G. Degliesposti, M. Q. Dong, N. Edinger, C. Emanuelsson, M. Gay, M. Götze, F. Gomes-Neto, F. C. Gozzo, C. Gutierrez, C. Haupt, A. J. R. Heck, F. Herzog, L. Huang, M. R. Hoopmann, N. Kalisman, O. Klykov, Z. Kukacka, F. Liu, M. J. MacCoss, K. Mechtler, R. Mesika, R. L. Moritz, N. Nagaraj, V. Nesati, A. G. C. Neves-Ferreira, R. Ninnis, P. Novak, F. J. O'Reilly, M. Pelzing, E. Petrotchenko, L. Piersimoni, M. Plasencia, T. Pukala, K. D. Rand, J. Rappsilber, D. Reichmann, C. Sailer, C. P. Sarnowski, R. A. Scheltema, C. Schmidt, D. C. Schriemer, Y. Shi, J. M. Skehel, M. Slavin, F. Sobott, V. Solis-Mezarino, H. Stephanowitz, F. Stengel, C. E. Stieger, E. Trabjerg, M. Trnka, M. Vilaseca, R. Viner, Y. F. Xiang, S. Yilmaz, A. Zelter, D. Ziemianowicz, A. Leitner, A. Sinz, First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study. Anal Chem91, 6953-6961 (2019). https://doi.org/10.1021/acs.analchem.9b00658

Jaudzems, K., T. Polenova, G. Pintacuda, H. Oschkinat, A. Lesage, DNP NMR of biomolecular assemblies. J Struct Biol206, 90-98 (2019). https://doi.org/10.1016/j.jsb.2018.09.011

Jayapaul, J., L. Schröder, Nanoparticle-Based Contrast Agents for Xe-129 HyperCEST NMR and MRI Applications. Contrast Media Mol I2019, 9498173 (2019). Review, https://doi.org/10.1155/2019/9498173

Kampinga, H. H., C. Andreasson, A. Barducci, M. E. Cheetham, D. Cyr, C. Emanuelsson, P. Genevaux, J. E. Gestwicki, P. Goloubinoff, J. Huerta-Cepas, J. Kirstein, K. Liberek, M. P. Mayer, K. Nagata, N. B. Nillegoda, P. Pulido, C. Ramos, P. De los Rios, S. Rospert, R. Rosenzweig, C. Sahi, M. Taipale, B. Tomiczek, R. Ushioda, J. C. Young, R. Zimmermann, A. Zylicz, M. Zylicz, E. A. Craig, J. Marszalek, Function, evolution, and structure of J-domain proteins. Cell Stress Chaperon24, 7-15 (2019). Review, https://doi.org/10.1007/s12192-018-0948-4

Kasper, M. A., M. Glanz, A. Stengl, M. Penkert, S. Klenk, T. Sauer, D. Schumacher, J. Helma, E. Krause, M. C. Cardoso, H. Leonhardt, C. P. R. Hackenberger, Cysteine-Selective Phosphonamidate Electrophiles for Modular Protein Bioconjugations. Angew Chem Int Ed58, 11625-11630 (2019). https://doi.org/10.1002/anie.201814715

Kasper§, M. A., M. Glanz§, A. Oder, P. Schmieder, J. P. von Kries, C. P. R. Hackenberger, Vinylphosphonites for Staudinger-induced chemoselective peptide cyclization and functionalization. Chem Sci10, 6322-6329 (2019). https://doi.org/10.1039/c9sc01345h

Kasper, M. A., A. Stengl, P. Ochtrop, M. Gerlach, T. Stoschek, D. Schumacher, J. Helma, M. Penkert, E. Krause, H. Leonhardt*, C. P. R. Hackenberger*, Ethynylphosphonamidates for the Rapid and Cysteine-Selective Generation of Efficacious Antibody-Drug Conjugates. Angew Chem Int Ed58, 11631-11636 (2019). https://doi.org/10.1002/anie.201904193

Kesten§, C., A. Wallmann§, R. Schneider, H. E. McFarlane, A. Diehl, G. A. Khan, B. J. van Rossum, E. R. Lampugnani, W. G. Szymanski, N. Cremer, P. Schmieder, K. L. Ford, F. Seiter, J. L. Heazlewood, C. Sanchez-Rodriguez, H. Oschkinat*, S. Persson*, The companion of cellulose synthase 1 confers salt tolerance through a Tau-like mechanism in plants. Nat Commun10, 857 (2019). https://doi.org/10.1038/s41467-019-08780-3

Klose, M., J. E. Salloum, H. Gonschior, S. Linder, SNX3 drives maturation of Borrelia phagosomes by forming a hub for PI(3)P, Rab5a, and galectin-9. J Cell Biol218, 3039-3059 (2019). https://doi.org/10.1083/jcb.201812106

König, B., Y. C. Hao, S. Schwartz, A. J. R. Plested, T. Stauber, A FRET sensor of C-terminal movement reveals VRAC activation by plasma membrane DAG signaling rather than ionic strength. Elife8, e45421 (2019). https://doi.org/10.7554/eLife.45421

Kreis*, P., C. Gallrein, E. Rojas-Puente, T. G. A. Mack, C. Kroon, V. Dinkel, C. Willmes, K. Murk, S. Tom-Dieck, E. M. Schuman, J. Kirstein*, B. J. Eickholt*, ATM phosphorylation of the actin-binding protein drebrin controls oxidation stress-resistance in mammalian neurons and C. elegans. Nat Commun10, 486 (2019). https://doi.org/10.1038/s41467-019-08420-w

Le Roux, A. L., I. L. Mohammad, B. Mateos, M. Arbesu, M. Gairi, F. A. Khan, J. M. C. Teixeira, M. Pons, A Myristoyl-Binding Site in the SH3 Domain Modulates c-Src Membrane Anchoring. Iscience12, 194-203 (2019). https://doi.org/10.1016/j.isci.2019.01.010

Lehmann*, M., I. Lukonin, F. Noe, J. Schmoranzer, C. Clementi, D. Loerke, V. Haucke*, Nanoscale coupling of endocytic pit growth and stability. Sci Adv5, eaax5775 (2019). https://doi.org/10.1126/sciadv.aax5775

Li, X. L., S. W. Li, L. G. Yao, E. Mollo, M. Gavagnin, Y. W. Guo, The chemical and chemo-ecological studies on Weizhou nudibranch Glossodoris atromarginata. Magn Reson Chem,  (2019). https://doi.org/10.1002/mrc.4949

Liu, C. P., C. Y. Xie, J. X. Zhao, K. L. Ji, X. X. Lei, H. Sun*, L. G. Lou*, J. M. Yue*, Dysoxylactam A: A Macrocyclolipopeptide Reverses P-Glycoprotein-Mediated Multidrug Resistance in Cancer Cells. J Am Chem Soc141, 6812-6816 (2019). Article https://doi.org/10.1021/jacs.9b02259

Lozza, L., P. Moura-Alves, T. Domaszewska, C. L. Crespo, I. Streata, A. Kreuchwig, A. Puyskens, M. Bechtle, M. Klemm, U. Zedler, B. S. Ungureanu, U. Guhlich-Bornhof, A. B. Koehler, M. Staber, H. J. Mollenkopf, R. Hurwitz, J. Furkert, G. Krause, J. Weiner, A. Jacinto, I. Mihai, M. Leite-de-Moraes, F. Siebenhaar, M. Maurer, S. H. E. Kaufmann, The Henna pigment Lawsone activates the Aryl Hydrocarbon Receptor and impacts skin homeostasis. Sci Rep9, 10878 (2019). https://doi.org/10.1038/s41598-019-47350-x

Maglione, M., G. Kochlamazashvili, T. Eisenberg, B. Racz, E. Michael, D. Toppe, A. Stumpf, A. Wirth, A. Zeug, F. E. Müller, L. Moreno-Velasquez, R. P. Sammons, S. J. Hofer, F. Madeo, T. Maritzen, N. Maier, E. Ponimaskin, D. Schmitz, V. Haucke*, S. J. Sigrist*, Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses. Sci Rep9, 19616 (2019). https://doi.org/10.1038/s41598-019-56133-3

Marcinkowski, P., I. Hoyer, E. Specker, J. Furkert, C. Rutz, M. Neuenschwander, S. Sobottka, H. Sun, M. Nazaré, U. Berchner-Pfannschmidt, J. P. Von Kries, A. Eckstein, R. Schülein, G. Krause, A New Highly Thyrotropin Receptor-Selective Small-Molecule Antagonist with Potential for the Treatment of Graves' Orbitopathy. Thyroid29, 111-123 (2019). Article https://doi.org/10.1089/thy.2018.0349

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Stengl, A., M. Gerlach, M. A. Kasper, C. P. R. Hackenberger, H. Leonhardt, D. Schumacher, J. Helma, TuPPL: Tub-tag mediated C-terminal protein-protein-ligation using complementary click-chemistry handles. Org Biomol Chem17, 4964-4969 (2019). https://doi.org/10.1039/c9ob00508k

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