Current Research on Neurotransmission and Neuronal Membrane Dynamics

Further contributions:

  • Jäpel et al. Cell Rep. 2010
  • Helbig, I., Lopez-Hernandez, T., Shor, O., Galer, P. Ganesan, S., Pendziwiat, M., Rademacher, A., Ellis, C.A., Hümpfer, N., Schwarz, N., Seiffert, S., Peeden, J., Shen, J., Sterbova, K., Hammer, T.B., Moller, R.S., Shinde, D.N., Tang, S., Smith, L., Poduri, A., Krause, R., Benninger, F., Helbig, K.L., Haucke, V., Weber, Y.G. (2019) Am. J. Hum. Genet., 104, 1060-1072.
  • Gerth, F., Jäpel, M., Pechstein, A., Kochlamazashvili, G., Lehmann, M., Puchkov, D., Onofri, F., Benfenati, F., Nikonenko, A.G., Friedrich, K.,Shupliakov, O., Maritzen, T., Freund, C., Haucke, V. (2017) Intersectin associates with synapsin and regulates its nanoscale localization and function. Proc. Natl. Acad. Sci. USA, 114, 12057-12062.01
  • Jakob, B., Kochlamazashvili, G., Jäpel, M., Gauhar, A., Bock, H.H., Maritzen, T., Haucke, V. (2017) Intersectin 1 is a component of the Reelin pathway to regulate neuronal migration and synaptic plasticity in the hippocampus. Proc. Natl. Acad. Sci. USA, 114, 5533-5538.
  • Soykan, T., Maritzen, T., Haucke, V. (2016) Modes and mechanisms of synaptic vesicle recycling. Curr. Opin. Neurobiol., 39, 17-23.
  • Gimber, N., Tadeus, G., Maritzen, T., Schmoranzer, J., Haucke, V. (2015) Diffusional spread and confinement of newly exocytosed synaptic vesicle proteins. Nature Communications, 6, 8392 [DOI: 10.1038/ncomms9392]
  • Jung, S.Y., Maritzen, T., Wichmann, C., Jing, Z., Neef, A., Revelo, N.H., Al-Moyed, H., Meese, S., Wojcik, S.M., Panou, I., Bulut, H., Schu, P., Ficner, R., Reisinger, E., Rizzoli, S.O., Haucke, V.#, Moser, T.# (2015) Disruption of adaptor protein 2μ (AP-2μ) in cochlear hair cells impairs vesicle reloading of synaptic release sites and hearing. EMBO J, 34, 2686-2702.
  • Lehmann, M., Gottschalk, B., Puchkov, D., Schmieder, P., Schwagerus, S., Hackenberger, C.P., Haucke, V., Schmoranzer, J. (2015) Multicolor 'caged' dSTORM resolves the ultra-structure of synaptic vesicles in the brain. Angew. Chem. 54, 13230-13235.
  • Kaempf N., Kochlamazashvili G., Puchkov D., Maritzen T., Bajjalieh S.M., Kononenko N.L., Haucke V. (2015) Proc Natl Acad Sci U S A, 112, 7297-7302.
  • Podufall, J,. Tian, R., Knoche, E., Puchkov, D., Walter, A.M., Rosa, S., Quentin, C., Vukoja, A., Jung, N., Lampe, A., Wichmann, C., Böhme, M., Depner, H., Zhang, Y.Q., Schmoranzer, J., Sigrist, S.J., Haucke, V. (2014) A presynaptic role for the cytomatrix protein GIT in synaptic vesicle recycling. Cell Reports, 7, 1417-1425.
  • Wilhelm, B.G., Mandad, S., Truckenbrodt, S., Kröhnert, K., Schäfer, C., Rammner, B., Koo, S.J., Claßen, G.A., Krauss, M., Haucke, V., Urlaub, H., Rizzoli, S. O. (2014) Composition of Synaptic Boutons Reveals the Amounts of Vesicle Trafficking Proteins. Science, 344, 1023-1028.
  • Kononenko, N., Diril, M.K., Puchkov, D., Kintscher, M., Koo, S.J., Pfuhl, G, Winter, Y., Wienisch, M., Klingauf, J., Breustedt, J., Schmitz, D., Maritzen, T., Haucke, V. (2013) Compromised fidelity of endocytic synaptic vesicle protein sorting in the absence of stonin 2. Proc Natl Acad Sci U S A, 110, E526-E535.
  • Sakaba, T., Kononenko, N., Bacetic, J., Pechstein, A., Schmoranzer, J., Yao, L., Barth, H., Shupliakov, O., Kobler, O., Aktories, K., Haucke, V. (2013) Fast neurotransmitter release regulated by the endocytic scaffold intersectin. Proc Natl Acad Sci U S A, 110, 8266-71.
  • Puchkov, D. and Haucke, V. (2013) Greasing the synaptic vesicle cycle by membrane lipids. Trends Cell Biol., 23, 493–503.
  • von Kleist, L., Stahlschmidt, W., Bulut, H., Gromova, K., Puchkov, D., Robertson, M., MacGregor, K.A., Tomlin, N., Pechstein, A., Chau, N., Chircop, M., Sakoff, J., von Kries, J., Saenger, W., Kräusslich, H.-G., Shupliakov, O., Robinson, P., McCluskey, A., Haucke, V. (2011) Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition. Cell, 146, 471-484.
  • Koo, S.Y., Markovic, S., Puchkov, D., Mahrenholz, C., Beceren-Braun, F., Maritzen, T., Dernedde, J., Volkmer, R., Oschkinat, O., Haucke, V. (2011) SNARE motif-mediated sorting of synaptobrevin by the endocytic adaptors CALM and AP180 at synapses. Proc. Natl. Acad. Sci. USA, 108, 13540-13545.
  • Pechstein, A., Bacetic, J., Vahedi-Faridi, A., Gromova, K., Sundborger, A., Tomlin, N., Krainer, N., Vorontsova, O., Schäfer, J.G., Owe, S.G., Cousin, M.A., Saenger, W., Shupliakov, O., Haucke, V. (2010) Regulation of synaptic vesicle recycling by complex formation between intersectin 1 and the clathrin adaptor complex AP2. Proc. Natl. Acad. Sci. USA, 107, 4206-4211.
  • Wieffer, M., Maritzen, T., and Haucke, V. (2009) SnapShot: Endocytic trafficking at the plasma membrane. Cell 137, 382.e1-3.
  • Jung, N., Wienisch, M., Gu, M., Rand, J.B., Müller, S.L., Krause, G., Jorgensen, E.M., Klingauf, J., Haucke, V. (2007) Molecular basis of synaptic vesicle cargo recognition by the endocytic sorting adaptor stoning 2. J. Cell. Biol., 179, 1497-1510.
  • Diril, M. K., Wienisch, M., Jung, N., Klingauf, J., and Haucke, V. (2006) Stonin 2 is an AP-2-dependent endocytic sorting adaptor for synaptotagmin internalization. Dev. Cell 10, 233-244.

Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V. (FMP)
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