Membrane Traffic and Cell Motility (Tanja Maritzen)

Selected Publications

Maritzen T, Haucke V. Coupling of Exocytosis and Endocytosis at the Presynaptic Active Zone. Neurosci Res. 2018 Feb; 127:45-52. doi: 10.1016/j.neures.2017.09.013

Gerth F, Jäpel M, Pechstein A, Kochlamaszashvili G, Lehmann M, Puchkov D, Onofri F, Benfenati F, Nikonenko AG, Maritzen T, Freund C, Haucke V. Intersectin associates with synapsin and regulates its nanoscale localization and function. Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):12057-12062

Kaempf N, Maritzen T. Safeguards of Neurotransmission: Endocytic Adaptors as Regulators of Synaptic Vesicle Composition and Function. Front Cell Neurosci. 2017 Oct 11; 11:320

Mertins P, Przybylski D, Yosef N, Qiao J, Clauser K, Raychowdhury R, Eisenhaure TM, Maritzen T, Haucke V, Satoh T, Akira S, Carr SA, Regev A, Hacohen N, Chevrier N. An integrative framework reveals signaling-to-transcription events in Toll-like receptor signaling. Cell Rep. 2017 Jun 27;19(13):2853-2866

Jakob B, Kochlamazashvili G, Jäpel M, Gauhar A, Bock H, Maritzen T, Haucke V. Intersectin 1 is a component of the Reelin pathway to regulate neuronal migration and synaptic plasticity in the hippocampus. Proc Natl Acad Sci USA. 2017; 114(21):5533-5538

Kononenko NL, Claßen GA, Kuijpers M, Puchkov D, Maritzen T, Tempes A, Malik AR, Skalecka A, Bera S, Jaworski J, Volker Haucke. Retrograde transport of TrkB-containing autophagosomes via the endocytic adaptor AP-2 mediates neuronal complexity and prevents neurodegeneration. Nat Commun. 2017; 8:14819.

Soykan T, Maritzen T, Haucke V. Modes and mechanisms of synaptic vesicle recycling. Curr Opin Neurobiol. 2016 Mar 23;39:17-23.

Schachtner H, Weimershaus M, Stache V, Plewa N, Legler DF, Höpken UE, Maritzen T. Loss of Gadkin Affects Dendritic Cell Migration In Vitro.PLoS One. 2015 Dec 1;10(12)

Koo SJ, Kochlamazashvili G, Rost B, Puchkov D, Gimber N, Lehmann M, Tadeus G, Schmoranzer J, Rosenmund C, Haucke V*, Maritzen T*. Vesicular Synaptobrevin/VAMP2 Levels Guarded by AP180 Control Efficient Neurotransmission. Neuron. 2015 Oct 21;88(2):330-44.

Gimber N, Tadeus G, Maritzen T, Schmoranzer J, Haucke V. Diffusional spread and confinement of newly exocytosed synaptic vesicle proteins. Nat Commun. 2015 Sep 24;6:8392.

Jung S, Maritzen T, Wichmann C, Jing Z, Neef A, Revelo NH, Al-Moyed H, Meese S, Wojcik SM, Panou I, Bulut H, Schu P, Ficner R, Reisinger E, Rizzoli SO, Neef J, Strenzke N, Haucke V, Moser T. Disruption of adaptor protein 2μ (AP-2μ) in cochlear hair cells impairs vesicle reloading of synaptic release sites and hearing. EMBO J. 2015 Oct 7.

Feutlinske F, Browarski M, Ku MC, Trnka P, Waiczies S, Niendorf T, Stallcup WB, Glass R, Krause E, Maritzen T. Stonin1 mediates endocytosis of the proteoglycan NG2 and regulates focal adhesion dynamics and cell motility. Nat Commun. 2015 Oct 5;6:8535.

Kaempf N, Kochlamazashvili G, Puchkov D, Maritzen T, Bajjalieh SM, Kononenko NL, Haucke V. Overlapping functions of stonin 2 and SV2 in sorting of the calcium sensor synaptotagmin 1 to synaptic vesicles. Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7297-302.

Maritzen T, Schachtner H, Legler DF. On the move: endocytic trafficking in cell migration. Cell Mol Life Sci. 2015 Jun;72(11):2119-34.

Rust MB, Maritzen T. Relevance of presynaptic actin dynamics for synapse function and mouse behavior. Exp Cell Res. 2015 Jul 15;335(2):165-71.

Pechstein A, Gerth F, Milosevic I, Jäpel M, Eichhorn-Grünig M, Vorontsova O, Bacetic J, Maritzen T, Shupliakov O, Freund C, Haucke V. Vesicle uncoating regulated by SH3-SH3 domain-mediated complex formation between endophilin and intersectin at synapses. EMBO Rep. 2015 Feb;16(2):232-9.

Seifert W, Kühnisch J, Maritzen T, Lommatzsch S, Hennies HC, Bachmann S, Horn D, Haucke V. Cohen syndrome-associated protein COH1 physically and functionally interacts with the small GTPase RAB6 at the Golgi complex and directs neurite outgrowth. J Biol Chem. 2015 Feb 6;290(6):3349-58.

Kononenko NL, Puchkov D, Classen GA, Walter AM, Pechstein A, Sawade L, Kaempf N, Trimbuch T, Lorenz D, Rosenmund C, Maritzen T, Haucke V. Clathrin/AP-2 mediate synaptic vesicle reformation from endosome-like vacuoles but are not essential for membrane retrieval at central synapses. Neuron. 2014 Jun 4;82(5):981-8.

Kononenko N, Diril MK, Puchkov D, Kintscher M, Koo SJ, Pfuhl G, Winter Y, Wienisch M, Klingauf J, Breustedt J, Schmitz D, Maritzen* T, Haucke* V. Compromised fidelity of endocytic synaptic vesicle protein sorting in the absence of stonin 2. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):526-35.

Maritzen T, Zech T, Schmidt MR, Krause E, Machesky LM, Haucke V. Gadkin negatively regulates cell spreading and motility via sequestration of the actin-nucleating ARP2/3 complex. Proc Natl Acad Sci U S A. 2012 Jun 26; 109(26):10382-7.

Maritzen T, Koo SJ, Haucke V. Turning CALM into excitement: AP180 and CALM in endocytosis and disease. Biol Cell. 2012 May 29

Koo SJ, Markovic S, Puchkov D, Mahrenholz CC, Beceren-Braun F, Maritzen T, Dernedde J, Volkmer R, Oschkinat H, Haucke V. SNARE motif-mediated sorting of synaptobrevin by the endocytic adaptors clathrin assembly lymphoid myeloid leukemia (CALM) and AP180 at synapses. Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13540-5.

Laulagnier K, Schieber NL, Maritzen T, Haucke V, Parton RG, Gruenberg J. Role of AP1 and Gadkin in the traffic of secretory endo-lysosomes. Mol Biol Cell. 2011 Jun; 22(12):2068-82.

Maritzen T & Haucke V. Gadkin – A novel link between endosomal vesicles and microtubule tracks. Communicative & Integrative Biology. 2010 Jul/ Aug; 3:4, 1-4.

Maritzen* T, Schmidt* MR, Kukhtina V, Higman V, Strauss H, Volkmer R, Oschkinat H, Dotti CG, and Haucke V. A novel subtype of AP-1 binding motif within the palmitoylated TGN/endosomal accessory protein Gadkin/g-BAR. J Biol Chem. 2010 Feb 5; 285(6):4074-86.

Schmidt* MR, Maritzen* T, Kukhtina V, Higman VA, Doglio L, Barak NN, Strauss HM, Oschkinat H, Dotti CG, Haucke V. Regulation of endosomal membrane traffic by a Gadkin/AP-1/kinesin KIF5 complex. Proc Natl Acad Sci U S A. 2009 Aug 21.

Maritzen T, Podufall J, Haucke V. Stonins-Specialized Adaptors for Synaptic Vesicle Recycling and Beyond? Traffic. 2009 Aug 4.

Wieffer M, Maritzen T, Haucke V. SnapShot: Endocytic trafficking. Cell. 2009 Apr 17;137(2):382.e1-3.

Rumpf J, Simon B, Jung N, Maritzen T, Haucke V, Sattler M, Groemping Y. Specificity of EH-ligand interactions: a high affinity complex between Eps15 and Stonin2 via two distinct binding sites on EH2. EMBO J. 2008 Feb 6; 27(3):558-69.

Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V. (FMP)
Campus Berlin-Buch
Robert-Roessle-Str. 10
13125 Berlin, Germany
+4930 94793 - 100 
+4930 94793 - 109 (Fax)
info(at)fmp-berlin.de

Like many sites, we use cookies to optimize the user's browsing experience. Data Protection OK