Andrew Plested
Heisenberg Professor of Cellular Biophysics, Humboldt Universität zu Berlin


Leibniz-Forschungsinstitut für Molekulare Pharmakologie
Robert-Rössle-Str. 10
13125 Berlin

Tel.: +49 (0) 30 94793-245 
                      -322 (Lab.)

We don't have a fax

plested [at]

Molecular Neuroscience and Biophysics (Andrew Plested)

In the Plested lab, we are interested in ion channel receptors and fast signalling in the nervous system. Receptors that are found at synapses between nerve cells have formed the backbone of our research for some years. The activation of these complex macromolecular machines is triggered by neurotransmitters in a fraction of a second. Our objective is to understand the relationship between the molecular structure of a given receptor (its shape) and its activity (what it does). More recently, we have become interested in the relation between receptor properties and synaptic signalling. 

We are members of the Humboldt University Institute for Biology, the NeuroCure Cluster of Excellence, and the Leibniz-Institut für Molekulare Pharmakologie (FMP). Our laboratories are located in the Marthe-Vogt-Haus (Haus 81) at the Campus Berlin Buch. If you would like to contact us, please write to the email address on the right.

Latest News

10.12.18 Our team from the Humboldt University was one of thirteen successful applicants in the DFG Innovative-Light-Microscopy competition. A modular, multichannel 2-photon microscope for optogenetics and imaging of neuronal activity will be built in the HU-Berlin Biophysics department. If you're interested to work with us on this project, get in touch!

6.12.18 Auxiliary subunits keep AMPA receptors compact during activation and desensitization

Jelena's paper about how Stargazin determines AMPA receptor structural dynamics is online at eLife. Congrats JB! You can read more about Jelena in this profile at Nature Communications.

1.7.18 Kordelia Hummel has joined the Plested lab to support our work on glutamate receptors. Kordelia comes to us from the Uckert lab at the MDC-Berlin, bringing her expertise in cell culture, biochemistry and molecular biology. We are very happy to welcome you to AG Plested, Kordelia!

15.5.18 Sabrina Mischke has joined us to work on glutamate receptor spectroscopy and imaging. Sabrina is a German native and a physicist by training. Welcome to Berlin, Sabrina!

1.4.18 AMPA receptors - mechanisms of auxiliary protein action

Clarissa and Andrew wrote a review about how auxiliary subunits work for a special issue of the new journal Current Opinions in Physiology. The AMPA-Receptor (structure from Twomey et al) made the cover too. 


Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V. (FMP)
Campus Berlin-Buch
Robert-Roessle-Str. 10
13125 Berlin, Germany
+4930 94793 - 100 
+4930 94793 - 109 (Fax)

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