Contact

Dr. Katina Lazarow

Phone: +49 (0)30 9406 3072
Mail: lazarow(at)fmp-berlin.de

What's new

Synthego Human Deubiquitinating Enzymes and Ubiquitin Ligases sgRNA Libraries are now available for screening! [March 2019]

Dharmacon Human ON‑TARGETplus SMARTpool  genome‑wide siRNA Library
now available for screening! [February 2018]

Dharmacon Human Edit-R crRNA library targeting 647 Ubiquitination Enzymes now available for screening! [September 2016]

Selected publication

Ullrich et al. eLife 2019

Screening Unit

RNAi and CRISPR-Cas9 Screening

The facility offers scientists from the FMP and MDC access to high-throughput screening with arrayed miRNA, siRNA and sgRNA libraries on the basis of a scientific collaboration.

Broad range of assays

State of the art equipment supports a broad range of assays in high-throughput formats, ranging from basic reporter assays to high-content screening campaigns. Instrumentation covers automated fluorescence microscopy, flow cytometry, luminescence and real-time kinetic fluorescence reading (see Technologies).

Full support in high-throughput screening

We operate on the basis of a scientific collaboration and offer support through all stages of a screening campaign: assay development and adaption to high-throughput screening, the actual wet-lab screen, data acquisition and quality assessment, statistical analysis as well as hit candidate selection.

Data processing

We are constantly advancing our in-house analysis, database and reporting tools to keep the platform updated. The integration of freely available open-source tools (e.g. KNIME Analytics Platform) and the development of our own analysis workflows enables us to meet the specific requirements of a multitude of biological questions.

Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V. (FMP)
Campus Berlin-Buch
Robert-Roessle-Str. 10
13125 Berlin, Germany
+4930 94793 - 100 
+4930 94793 - 109 (Fax)
info(at)fmp-berlin.de

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