FMP spin-offs

The creation of a new company / spin-off is a substantial challenge for both, the new entrepreneurs and the research institute as the origin of the technologies to be transferred. Once the legal, technical, and financial terms have been established the spin-off is ready to become independent.


In the near future, a spin-off having it’s business in the field of Antibody-Drug-Conjugates (ADCs) will be established:

Tubulis Technologies

Tubulis Technologies is currently a pre-start-up project affiliated with the Ludwig Maximilians University (LMU) Munich and the FMP. Tubulis Technologies aims to provide the next generation of highly defined, effective and stable ADCs. The company will focus on the development of cutting-edge technologies for site-specific antibody conjugation, thereby providing the ‘molecular glue’ for efficient drug attachment. For this purpose, it will integrate biotechnological and chemical expertise with proprietary know how to promote ADC homogeneity and overall stability, ultimately widening the therapeutic window for ADCs.


In 2000, two companies have been founded by FMP researchers:

PSF Biotech AG

Area of expertise: structural genomics and target discovery

The company provided service in the field of lead structure optimisation, structural characterisation and validation of target proteins as well as production of recombinant proteins.

Combinature Biopharm AG

Area of expertise: combinatorial biosynthesis of natural compound libraries, pre-clinical development of antibiotic compounds  

In August 2006, Combinature Biopharm AG was acquired by MerLion Pharmaceuticals Pte Ltd (MerLion) of Singapore, the world’s leading natural products based drug discovery company. MerLion’s headquarters and drug discovery research centre is based in Singapore, drug development of its anti-infective programmes and nuclear magnetic resonance screening activities are being conducted from Berlin.

In June 2007, Evotec AG acquired the NMR Fragment-Based Drug Discovery Business from MerLion Pharmaceuticals' subsidiary, Combinature Biopharm AG.

Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V. (FMP)
Campus Berlin-Buch
Robert-Roessle-Str. 10
13125 Berlin, Germany
+4930 94793 - 100 
+4930 94793 - 109 (Fax)

Like many sites, we use cookies to optimize the user's browsing experience. Data Protection OK