„”
Dr.
Structure-Based Design of Xanthine-Imidazopyridines and -Imidazothiazoles as Highly Potent and In Vivo Efficacious Tryptophan Hydroxylase Inhibitors
Journal of Medicinal Chemistry 2023
read onlineSmall Molecules Targeting Human UDP‐GlcNAc 2‐Epimerase
ChemBioChem 2023
read onlineSmall molecule inhibiting microglial nitric oxide release could become a potential treatment for neuroinflammation
PLOS ONE 2023
read onlineDiscovery of tetrazolo-pyridazine-based small molecules as inhibitors of MACC1-driven cancer metastasis
Biomedicine & Pharmacotherapy 2023
read onlineStructural Basis for Highly Selective Class II Alpha Phosphoinositide-3-Kinase Inhibition
Journal of Medicinal Chemistry 2023
read onlineStructure-Based Design of Xanthine-Benzimidazole Derivatives as Novel and Potent Tryptophan Hydroxylase Inhibitors
Journal of Medicinal Chemistry 2022
read onlineProbing Factor Xa Protein–Ligand Interactions: Accurate Free Energy Calculations and Experimental Validations of Two Series of High-Affinity Ligands
Journal of Medicinal Chemistry 2022
read onlineTopical inflammasome inhibition with disulfiram prevents irritant contact dermatitis
Clinical and Translational Allergy 2021
read onlineEnhanced Properties of a Benzimidazole Benzylpyrazole Lysine Demethylase Inhibitor: Mechanism-of-Action, Binding Site Analysis, and Activity in Cellular Models of Prostate Cancer
Journal of Medicinal Chemistry 2021
read onlineSmall-Molecule Lysophosphatidic Acid Receptor 5 (LPAR5) Antagonists: Versatile Pharmacological Tools to Regulate Inflammatory Signaling in BV-2 Microglia Cells
Frontiers in Cellular Neuroscience 2019
read onlineEU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
SLAS Discovery 2019
read onlineA New Highly Thyrotropin Receptor-Selective Small-Molecule Antagonist with Potential for the Treatment of Graves' Orbitopathy
Thyroid 2019
read onlineUse of a sequential high throughput screening assay to identify novel inhibitors of the eukaryotic SRP-Sec61 targeting/translocation pathway
PLOS ONE 2018
read onlineCellFy: A Cell-Based Fragment Screen against C-Type Lectins
ACS Chemical Biology 2018
read onlineIdentification of a Novel Benzimidazole Pyrazolone Scaffold That Inhibits KDM4 Lysine Demethylases and Reduces Proliferation of Prostate Cancer Cells
SLAS Discovery 2017
read onlineStatin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1
PLOS Biology 2017
read onlineSmall-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity
Nature Neuroscience 2017
read onlinePharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin lymphoma
Blood 2017
read onlineA Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis
Cancer Research 2016
read onlineTemperature dependence of cross-effect dynamic nuclear polarization in rotating solids: advantages of elevated temperatures
Physical Chemistry Chemical Physics 2016
read onlineDesign of a General‐Purpose European Compound Screening Library for EU‐OPENSCREEN
ChemMedChem 2014
read onlineTractable synthesis of multipurpose screening compounds with under-represented molecular features for an open access screening platform
Molecular Diversity 2014
read onlineNeurotoxin II Bound to Acetylcholine Receptors in Native Membranes Studied by Dynamic Nuclear Polarization NMR
Journal of the American Chemical Society 2011
read onlineAspartic Acid Proteases as Therapeutic Targets. Edited by Arun K. Ghosh.
ChemMedChem 2011
read onlineZwei neue privilegierte Bausteine und ein unerwarteter Bindungsmodus für HIV‐Protease‐Inhibitoren †
Angewandte Chemie 2005
read onlineAn Old Target Revisited: Two New Privileged Skeletons and an Unexpected Binding Mode For HIV‐Protease Inhibitors †
Angewandte Chemie 2005
read onlineHydroxyethylene sulfones as a new scaffold to address aspartic proteases
Journal of medicinal chemistry 2005
read onlineDde-protected PNA monomers, orthogonal to Fmoc, for the synthesis of PNA–peptide conjugates
Tetrahedron 2005
read onlineThe Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) is part of the Forschungsverbund Berlin e.V. (FVB), which legally represents seven non-university research institutes - members of the Leibniz Association - in Berlin.
Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V. (FMP)
Campus Berlin-Buch
Robert-Roessle-Str. 10,
13125 Berlin, Germany